I am a laboratory-trained nutritional scientist and my current research focuses on early phase clinical development of dietary cancer chemopreventive agents with an emphasis on agents for breast cancer prevention. I have developed novel assays to quantify the bioactive food components limonene and perillic acid from biological tissues for quantification with GC-MS and LC-MS. I have been involved with early phase clinical trials of cancer chemopreventive agents, including limonene, resveratrol, and green tea polyphenols. Through my R25T postdoctoral fellowship, I obtained some training in metabolomics at Imperial College, London using UPLC-MS. We have since continued this work by conducting metabolomic profiling in breast cancer patients on limonene intervention (work presented at the AACR 2013 annual meeting). Also in collaboration with Imperial College, we have initiated efforts to characterize the metabolite composition of nipple aspirate fluid (NAF) using NMR and GC-MS in an effort order to understand the local breast environment. I am currently lead in a collaboration with Waters Corporation to continue this metabolomics work using the Xevo G2S UPLC-QToF system. I have expanded my work in metabolite profiling to include analysis of the oxylipin cascade (topic of submitted abstract) in relationship to solid tumors (colon and breast) as well as to clinical outcomes such as pain. My long-term research goals involve using metabolomics to investigating intermediate biomarkers of cancer risk (e.g. inflammation and metabolism) as a way to improve screening and agents for cancer prevention.