Jean-Pierre Trezzi is a PhD student in the Metabolomics Group at the Luxembourg Centre for Systems Biomedicine under supervision of Dr. Karsten Hiller and at the Integrated Biobank of Luxembourg under supervision of Dr. Fay Betsou. He obtained his double Bachelor’s degree in Molecular and Cellular Biology at the Catholic University of Louvain in Belgium and at the University of Luxembourg. Later on, he obtained his Master’s degree in Integrated Systems Biology at the University of Luxembourg. His master thesis versed on delineating metabolic biomarker profiles for quality control and sample classification. His current work focusses on the identification of disease-specific biomarkers in human body fluids via mathematical modelling approaches and biobanking. Dr Karsten Hiller is an FNR-ATTRACT fellow and the head of the Metabolomics Group at the Luxembourg Centre for Systems Biomedicine. He obtained his diploma in Biology and Computer Science at the University of Braunschweig. Later on, he had an appointment as a postdoc in the group of Gregory Stephanopoulos at the department of Chemical Engineering, MIT where he worked on stable-isotope assisted metabolomics and cancer metabolism. In addition to standard metabolomics procedures, his group applies and develops stable-isotope assisted and non-targeted technologies to highlight the dynamic (flux) dimension of metabolism. In complement to metabolic flux analysis, this approach provides a non-targeted fingerprint of enzyme-activities and has successfully been applied to unravel not expected metabolic features.