48. Automated Picoliter to Nanoliter Sample Deposition for Mass Spectrometry
Poster: Tue 6:30-7:30PM
Glen Donald
Glen Donald, SonoPlot
Many of the current techniques for depositing sample for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry require a considerable amount of sample, produce large and inhomogeneous spots, and may result in broad peaks under analysis. The GIX Microplotter® instrument’s ultrasonically actuated fluid dispensing technology deposits consistent, uniform spots of analyte and matrix as small as 20 microns in diameter. These small spots conserve precious sample and allow for high density arraying on the target. In one experiment, we observed 20-micron-wide spots generating sharper and more intense peaks than those wider than 70 microns.