MSACL Conference Schedule

MSACL Conference Schedule
Nov 1-5, 2008

Saturday Nov 1
Short Courses
9 AM - 12 PM LC/MS: Practical Aspects
Lead: Jack Henion
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Lead: Russ Grant
Noon LUNCH
1 - 4 PM LC/MS: Practical Aspects
Lead: Jack Henion
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Lead: Russ Grant

Sunday Nov 2
Short Courses
9 AM - 12 PM LC/MS: Practical Aspects
Lead: Jack Henion
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Lead: Russ Grant
Introduction to Mass Spectrometry
Lead: Ken Busch
Metabolomics
Lead: Gary Siuzdak
Noon LUNCH
1 - 4 PM LC/MS: Practical Aspects
Lead: Jack Henion
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Lead: Russ Grant
Introduction to Mass Spectrometry
Lead: Ken Busch
Metabolomics
Lead: Gary Siuzdak
5 - 8 PM RECEPTION IN EXHIBIT HALL
8 - 8:30 PM
Sunday Evening Plenary
Vitamin D Assays: What You Measure Matters
LJ Deftos, MD, JD

Monday Nov 3
8:00 AM Opening Welcome and Remarks
David Herold
Plenary Session
Chair: Ravinder Singh
8:10 AM Mass Spectrometry Can Improve Clinical Chemistry and Patient Care
Jack Henion
8:55 AM Mass Spectrometry in Clinical Diagnostics-David versus Goliath
Russ Grant
9:40 AM BREAK
Small Molecule Analytes - 1
Chair: Nigel Clarke
Tissue Imaging by Mass Spectrometry
Chair: Pierre Chaurand
10:00 AM High Sensitivity Quantitation of 1,25-Dihydroxy Vitamin D3 (Calcitriol) in Human Plasma Using Online Sample Preparation and Triple Quadrupole Mass Spectrometry
H.Ghobarah
MALDI Imaging Mass Spectrometry of Tissue Sections: State of the Art and Future Directions
Pierre Chaurand
10:30 AM Determination of Plasma Aldosterone Using Liquid Chromatography-Tandem Mass Spectrometry with Semi-Automated On-Line Sample Preparation
Paul Taylor
Biomarker Identifications in Frozen and Umfix Processed Prostate Cancer Tissues Using MALDI Mass Spectrometry Imaging
Richard Drake
11:00 AM Improvement of Sample Clean-Up for Clinical Chemical LC-MS Analysis of Small Molecules in Biofluids
Karl Boos
Tissue and Biofluid Imaging with Nanostructure-Initiator Mass Spectrometry (NIMS)
Gary Siuzdak
11:30 AM Transition from Immunoassays to Mass Spectrometry Assays: What Should We Expect?
Frank Z. Stanczyk
Imaging Supported Membranes Beyond The Diffraction Limit
Steven Boxer
Noon LUNCH / POSTERS / EXHIBITS
Environment and Chemical Disaster
Chair: Bob Kobelski
Proteomics
Chair: Ron Hendrickson
3:00 PM A High Throughput Method for the Analysis of Lewisite Metabolites in Urine.
Rayman Stanelle
Proteomics - From Basic Research to the Clinic
Ron Hendrickson
3:30 PM Rapid Population Screening for Exposure to Methyl Isocyanate and Related Compounds.
Bonnie Taffe
Quality Control for Highly Multiplexed Clinical Proteomics
Steve Master
4:00 PM Quantitation of Tetramine in Urine
Elizabeth Hamelin
Discovery and Validation of a Cancer Biomarker: From Technology Development to Clinical Application
Sushmita "Mimi" Roy
4:30 pM Simultaneous Characterization of Warfarin, Hydroxywarfarins, and Warfarin Glucuronides in Human Urine
Jeffery Moran
Targeted Multiplexed Protein Expresion Profiling Using MRM: Studying Biological Variation of Plasma Protein Levels Using a Twin Cohort
Christie Hunter
5 - 8 PM RECEPTION IN EXHIBIT HALL / POSTERS
8 - 9 PM
Monday Evening Workshops
MSACL'09 Organizing Committee
Chair: David Herold
Metabolomics and Inborn Errors
Chair: Gary Siuzdak
Regulations and Standards
Chair: Hubert Vesper
Proteins, Proteomics and Disease Markers
Chair: Andy Hoofnagle
Small Molecule, Tox, Environmental
Chair: Russ Grant
TBA
TBA

Tuesday Nov 4
Plenary Session
Chair: Alan Rockwood
8:00 AM To Infinity, and Beyond! The Clinical Mass Spectrometry Space
Don Chace
8:45 AM Tools for Accurate Measurement of Candidate Biomarkers in Plasma: Development of Multiplexed MS-Based SISCAPA Assays
Leigh Anderson
9:30 AM BREAK
Inborn Errors in Metabolism
Chair: Don Chace
Proteins
Chair: Andy Hoofnagle
10:00 AM High Throughput Quantitative Analysis of Acylcarnitines and Amino Acids by MADI-Triple Quadrupole Mass Spectrometry
Jay Corr
Tumor Marker Quantification by Mass Spectrometry: First Steps with Thyroglobulin
Andy Hoofnagle
10:30 AM Newborn Screening by a Non-derivatized Tandem Mass Spectrometry Assay
Alex Cherkasskiy
Mapping Protein Microheterogeneity: Applications in the Development of Biomarker for Type 2 Diabetes
Randy Nelson
11:00 AM Newborn Screening for Congenital Adrenal Hyperplasia Using Liquid Chromatography Tandem Mass Spectrometry
Mike Morris
Development and Optimization of the Reference Measurement Procedure for HbA1C by HPLC-MS
Patricia Kaiser
11:30 AM Identification and Quantification of Urinary Acylcarnitines by UPLC-MS/MS
Azeret Zuniga
Plasma Renin Activity Assay by LC-MS/MS: Dude! Where's my Peptide?
Cory Bystrom
Noon LUNCH / POSTERS / EXHIBITS
Metabolomics
Chair: Gary Siuzdak
Regulations and Standards
Chair: Hubert Vesper
3:00 PM Metabolomics on Stem-Cell- Based Therapy
Oscar Yanes
Mass Spectrometry in Clinical Laboratory Standardization and Routine Clinical Laboratory Applications
Hubert Vesper
3:30 PM The Application of a Metabolomics Dataset Toward the Understanding of Prostate Cancer
Chris Beecher
Establishing the Metrological Basis: The Work of NIST on Establishing Traceability in Laboratory Medicine
David M. Bunk
4:00 PM Metabolomics Reveals Large Effect of Gut Microflora on Host Biochemistry and Subsequent Activation of a Host Response
Eric Peters
Reference Laboratories and Laboratory Networks Linking the Metrological Basis to Measurement Results
Maria Ospina
4:30 pM A Global Peptide Profiling Approach To Identify Endogenous Peptide Substrate Interactions
Alan Saghatelian
Bad Science: The Instrumental Data in the Floyd Landis Case
Robert Blackledge
5 - 8 PM RECEPTION IN EXHIBIT HALL / POSTERS
8:00 PM
Presidential Election Night

Wednesday Nov 5
Toxicology
Chair: Alan Wu
Metabolomics - 2
Chair: Josh Rabinowitz
8:00 AM Mass Spectrometry in Toxicology: Broad Spectrum Drug Screening with Quadrupole and Ion Trap Mass Spectrometry
Kara Lynch
Using Metabolomics of Animal Models to Understand Complex Human Biochemistry and Disease
William Wikoff
8:30 AM Rapid Blood Drug Screen Using Ultra Performance Liquid Chromatography - Time of Flight Mass Spectrometry (UPLC-TOF)
Scott Kriger
Drug Target Identification Via Systems-Level Metabolic Flux Profiling
Josh Rabinowitz
9:00 AM Ion Suppression and Other Interferences in the Qualitative and Quantitative LC-MS/MS Analysis of Biological Fluids
Tom Annesley
Leucine D7 Labeling of Human C-Peptide for Assessment of Real-Time Insulin Biosynthesis: In Vivo Silac Metabolic Studies
Eduard Rogatsky
9:30 AM Drug Testing to Support Physician and Healthcare Professional Programs
Alan Wu
Metabolomics Approach for Biomarker Discovery and Diagnostic Development
Don Rose
10:00 AM BREAK
Molecular Diagnostics
Chair: Steve Hofstadler
Disease Markers
Chair: Ryuji Kobayashi
10:30 AM Rapid Identification of Bacteria from Clinical Specimens Using MALDI-TOF MS
Markus Kostrzewa
Differential Neuroproteomics Reveal Characteristic Protein Expression Changes in Fulminant Multiple Sclerosis
Jonas Bergquist
11:00 AM High Throughput Characterization of Amplified Nucleic Acids By ESI-TOF Mass Spectrometry: Applications of the IBIS T5000 to Pathogen Detection and Characterization
Steve Hofstadler
Verification of Candidate Protein Biomarkers of Prostate Cancer by MRM Mass Spectrometry
Joanna Hunter
11:30 AM Targeted Proteomics of Influenza Viral Particles
Christopher M. Colangelo
Reference Intervals and Serum/Urine Correlation for Hepcidin 25
Reza Panahi
12:00 PM Nucleic Acid Analysis in Microbes and Viruses by MALDI-TOF MS
Christiane Honisch
Identifying Proteolytic Peptides in Thalassemic Red Blood Cells
Kai Tang
12:30 PM LUNCH WORKSHOPS
New Advances
Chair: Rob Fitzgerald
Small Molecule Analytes - 2
Chair: Russ Grant
2:00 PM Driving Biological Discovery Using Separations Coupled to Mass Spectrometry
John Yates
Mass Spectrometry as an Enabling Technology in the Clinical Laboratory
Nigel Clarke
2:30 PM Overlapping MS/MS Spectra and Disease Proteomics
Nuno Bandeira
Addressing The Challenges of Throughput and Selectivity With High Resolution LC and New Scan Wave MS/MS Technology
Robert Plumb
3:00 PM Aptamers for Analyte Enrichment in Clinical Samples
Sheri Wilcox
A Comparative Study of Three Mass Spectrometric Ionization Sources to Micro-Fluidic Technology Coupled with Tandem Mass Spectrometric Method
MP George
3:30 PM Translating Basic Discoveries for Early Detection and Clinical Mangement of Skeletal Disease
Darren Hillegonds
Problems and Pitfalls of Acylcarnitine Analysis on LC/MS/MS
Thomas Lynn
6 - 9 PM Reception and Mexican Fiesta Overlooking the Pacific