MSACL 2010 Conference

Feb 6-10, 2010

** FINAL SCHEDULE **

	Sunday Feb 7
7:00 AM	BREAKFAST (provided)
	Short Courses
9:00 AM	LC/MS: Practical Aspects Lead: Jack Henion	Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics Lead: Russ Grant
	Separations for the Masses Lead: Robert Kobelski	Metabolomics Lead: Gary Siuzdak
Noon	LUNCH
1:00 PM	LC/MS: Practical Aspects Lead: Jack Henion	Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics Lead: Russ Grant
	Separations for the Masses Lead: Robert Kobelski	Metabolomics Lead: Gary Siuzdak
5:00 PM	RECEPTION IN EXHIBIT HALL
	Sunday Evening Plenary Session Chair:
7:30 PM	From Vitamin D to Hormone D: A Consideration of What is Important for Good Health Anthony W. Norman University of California, Riverside Confirmed
8:30 PM	Hospitality Suite Palm I/II

	Monday Feb 8
7:00 AM	BREAKFAST (provided)
8:00 AM	Opening Remarks and Welcome David Herold VA Healthcare San Diego and University of California, San Diego
	Monday Morning Plenary Session Chair: David Herold
8:10 AM	Systems Medicine, Transformational Technologies and the Emergence of Predictive, Personalized, Preventive and Participatory (P4) Medicine Leroy Hood Institute for Systems Biology Confirmed
9:00 AM	From Bedside to Bench: How Clinical Mass Spectrometry is Turning Traditional Human Health Research Upside Down Dayan Goodenowe Phenomenome Confirmed
10:00 AM	COFFEE BREAK
	Small Molecule Analysis I Chair: Nigel Clarke Track 1	Therapeutic Metabolomics Chair: Gary Siuzdak Track 2	Proficiency Testing Chair: Robert Kobelski Track 3
10:30 AM	Ultra High-Throughput Quantitative LC-MS/MS in a Clinical Diagnostics Laboratory - Breaking the 2000 samples/system/day barrier Russ Grant Labcorp Confirmed	Therapeutic Metabolomics Identifies a New Treatment Preventing Chronic Neuoropathic Pain Gary Patti The Scripps Research Institute Confirmed	Newborn Screening by Tandem Mass Spectrometry: Global Harmonization of Practice and Performance through a Quality Assurance Program Victor De Jesus CDC Confirmed
11:00 AM	Performances of a method for the quantification of 1alpha,25(OH)2-Vitamin D3 in serum by LC-MSMS without derivatization. Bruno Casetta AB SCIEX Confirmed	Metabolomics Reveals a Novel Therapeutic for Multiple Sclerosis Leah P. Shriver The Scripps Research Institute Confirmed	LRN-C PT Program: Being Prepared and Proficient LCDR Rachael Schmidt NCEH/CDC Confirmed
11:30 AM	Development of a Small Volume Sampling Technique and LC-MS Orbitrap Assay for Pediatric Pharmacokinetic Studies of Fentanyl and its Metabolites Uwe Christians University of Colorado Denver Confirmed	Lipidomics: Pathway to Early Diagnosis and Treatment of Alzheimer's Disease Paul Wood Phreedom Pharma Confirmed	Proficiency Testing for Trace Elements in Clinical Matrices: the New York State Experience Patrick Parsons NY State Dept of Health Confirmed
	Poster Splash Various	Poster Splash Metabolomics	Poster Splash Various
12:00 PM	1. Comparison of TSQ Vantage, Exactive and LTQ Velos for Quantitative Analysis of 1,25 Dihydroxyvitamin D in Plasma Barbora Chindarkarova Thermo Scientific Confirmed 11. Quantitative Profiling of Bile Acids in Biofluids and Tissues: Compound Class Targeting in a Metabolomics Workflow. Ivana Bobeldijk TNO Quality of Life Confirmed 21. Quantification of 3-Hydroxyisovalerylcarnitine in Dried Blood Spots by Tandem Mass Spectrometry Varies by Method Timothy Lim CDC Confirmed
12:06 PM	3. Isotope Dilution Analysis of Cortisol, Androstenedione and 17-alpha-Hydroxyprogesterone on the Varian 320 LC/MS/MS to Screen for Congenital Adrenal Hyperplasia (CAH) in Newborns Brian Nies Varian Confirmed 13. A New Approach to the Analysis of Hydrophilic Metabolites in Clinical Samples Joseph Pesek San Jose State University Confirmed 23. Semi-Automated Robotic Analysis of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3 in Human Serum by Isotopic Dilution Liquid Chromatography Mass Spectrometry Madhu Chaudhary-Webb CDC Confirmed
12:12 PM	5. Improvements to the Quantitative Analysis of Amines and Amino Acids in Physiological Samples by LC/MS/MS using Isotope Coded Tags Scott Daniels Life Technologies Confirmed 15. Monitoring Metabolic Disease States Using a Combined Flow Injection LC-MSMS Assay Sascha Dammeier Biocrates Confirmed 25. Biomonitoring of Persistent Organic Pollutants in Humans Using Gas Chromatography-Mass Spectrometry F. Reber Brown California Environmental Protection Agency Confirmed
12:18 PM	7. Method Development Strategies For Ultra High-Throughput LC-MS/MS Analysis of Small Polar Molecules Utilizing HILIC Mechanisms Brain Rappold Labcorp Confirmed 17. In Search of Non-Invasive Biomarkers for Alcohol-Induced Liver Damage **MOVED TO TUESDAY 12:18 Track 1** Soumen K. Manna NCI Confirmed 27. Analysis of Samples From Inhalation Burn Injury Patients David Klein Texas Dept of State Health Services Confirmed
12:24 PM	9. Increased Bioanalytical Throughput Utilizing Fused Core Particle with Selective Phospholipid Depletion Rick Link Supelco/Sigma-Aldrich Confirmed 19. Metabolic Peptide Biomarkers: From Sample to Spectrum Jizu Yi BD Diagnostics Confirmed 29. Detection of Hydrogen Cyanide in Blood using GCMS with Headspace Sample Injection Megan McGuigan CDC Confirmed
12:30 PM	LUNCH (provided) Pick it up before attending a workshop. LUNCH & LEARN: Industrial Workshops 12:45 - 1:45 PM Developing Analytical QC Plans and Quality Systems PerkinElmer Track 1 Bayview II/III LC Tandem MS Method Development and Multiplexing for Clinical Analysis Agilent Track 2 Mission II/III Utility and Implementation of Mass Spectrometry for Molecular Histology, Toxicology and Microbial Identification Bruker Daltonics Track 3 Bayview I Research to Production - Next Gen Low and Ultrahigh Throughput LC/MS Solutions with Unparalleled Ease of Use in Research Thermo Scientific Track 4 Mission I EXHIBITS & POSTERS in the Exhibit Hall
	Small Molecule Analysis II Chair: Russ Grant Track 1	Computational, Statistical, and Epidemiological Considerations for MS in the Clinical Laboratory Chair: Steve Skates Track 2	Regulations and Standards Chair: Hubert Vesper Track 3
3:00 PM	Quantitative Underivatized Amino Acid Analysis - Development, Dimensionality, Data Reduction and Diagnostic Utility Brian Rappold Labcorp Confirmed	MS Assay Precision and Its Implication for Longitudinal Biomarkers Steve Skates Harvard Medical School Confirmed	LC-MS/MS Assay Compliance: What it Takes to Integrate Mass Spectrometry-Specific Criteria in your Laboratory Elizabeth G. Pattison ARUP Confirmed
3:30 PM	Very Long Chain Fatty Acid Analysis by UPLC-MS/MS for the Diagnosis of Inherited Peroxisomal Disorders Aiping Liu ARUP Confirmed	How to Reduce False Positive Study Results Due to Bias David Ransohoff University of North Carolina School of Medicine Confirmed	Development of a Candidate Reference Measurement Procedure for the Determination of Vitamin B6 in Human Serum Johanna E. Camara NIST Confirmed
4:00 PM	Mass Spectrometry-Based Analysis of the Pharmacokinetics and Intracellular Metabolism of Nucleoside Reverse Transcriptase Inhibitors Leon Coulier TNO Quality of Life Confirmed	The Evolution of It: Proteomics, Ovarian Cancer and Experimental Design Keith Baggerly M. D. Anderson Cancer Center Confirmed	Evaluation of Analytical Approaches for Compound Identification by LC-MS: a Study of the Alcohol Biomarker Ethyl Glucuronide (EtG) in Urine Anders Helander Karolinska Institutet Confirmed
	Poster Splash Various	Poster Splash Proteomics I	Poster Splash Various
4:30 PM	2. The Use of Turbulent Flow Chromatography for Direct Injection of Dried Blood Spot Incubations to Assay Lysosomal Syndrome Disorders (LSD) Joseph Herman ThermoFisher Scientific Confirmed 12. A Priori Recognition of Peptide Modification Using the Isotope Cluster Matthew T. Olson The Johns Hopkins Hospital Confirmed 22. The Nanoliter Pipette And Pipette MS? Drew Sauter Nanoliter Confirmed
04:36 PM	4. Simultaneous Quantitation of Immunosuppressants and Screening/Confirmation of Additional Substances with Drug Interaction Potential Lisa Sapp Applied Biosystems Confirmed 14. Analysis of Hemoglobin and Transthyretin Variants and Post-translational Modifications Using an LTQ-Orbitrap Top-down MS/MS Platform Roger Theberge Boston University School of Medicine Confirmed 24. Monitoring Buprenorphine Treatment and Compliance using LC-MS/MS Kara Lynch UCSF Confirmed
04:42 PM	6. Metabolic Profiling of Breath in Obstructive Lung Disease with Gas Chromatography Mass Spectrometry Maria Basanta University of Manchester Confirmed 16. The Use of Peptide Training Kits to Build, Verify, and Evaluate Multiplexed Protein Quantitation Assays for Cross-Laboratory Studies Scott Peterman Thermo Fisher Scientific Confirmed 26. Quantitation of Apolipoproteins in Human Serum Using Liquid Chromatography Mass Spectrometry Sean Agger University of Washington Confirmed
04:48 PM	8. Identification and Labeling Strategy for the Quantification of Acylcarnitines in Urine and Plasma Azeret Zuniga University of Alberta Confirmed 18. Dereplication and De Novo Sequencing of Nonribosomal Peptides Nuno Bandeira University of California San Diego Confirmed 28. Rapid Identification of Yeast-Like Pathogens Directly from Positive Blood Cultures Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Gongyi Shi Bruker Daltonics Confirmed
04:54 PM	10. Development and Validation of an Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) Method for Direct Monitoring of Argatroban Anticoagulation Marion L Snyder Brigham and Womens Hospital Confirmed 20. Multiple Reaction Monitoring Cubed (MRM3): A New Strategy for Clinical Validation of Putative Biomarkers in Crude Serum at Low nanogram/mL Level Jean-Philippe Charrier bioMerieux Confirmed 30. Measurement of Plasma Tranexamic Acid Levels in Coronary Artery Bypass Graft Patients Using a Novel Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Assay Charbel Abou-Diwan Emory University School of Medicine Confirmed
5:00 PM	RECEPTION IN EXHIBIT HALL / POSTERS
	Monday Evening Plenary Session Chair:
7:30 PM	Detection of Performance-Enhancing Drugs in Urine and Blood Larry Bowers U.S. Anti-Doping Agency (USADA) Confirmed
8:30 PM	Hospitality Suite Palm I/II

	Tuesday Feb 9
7:00 AM	BREAKFAST (provided)
	Tuesday Morning Plenary Session Chair: Russell Grant
8:15 AM	Building a More Reliable and Efficient Proteomic Biomarker Development Pipeline Christopher Kinsinger NCI Confirmed
9:00 AM	Advances in Laser Desorption Time-of-Flight Mass Spectrometry for Biological Applications Marvin Vestal Virgin Instruments Confirmed
10:00 AM	COFFEE BREAK
	Toxicology: Pain Management Chair: William Clarke Track 1	Discovery Proteomics Chair: Andy Hoofnagle Track 2	Protein Adduct Methods Chair: Rudolph Johnson Track 3
10:30 AM	Clinicians Perspective: How Lab Results are Used in Pain Management Joseph Shurman Confirmed	Progress Toward a Biomarker Discovery-to-Development Pipeline in Clinical Proteomics Steve Carr Broad Institute Confirmed	A New Method for Detecting and Quantifying Organophosphate Nerve Agent Exposure in Human Serum Jennifer Links Battelle Memorial Institute/CDC Confirmed
11:00 AM	Utility of Blood for Drug Testing in Support of Pain Management Clinics Gwen McMillin ARUP Confirmed	Lipoproteomics in Obesity and Insulin Resistance Andy Hoofnagle University of Washington Confirmed	Development of a GC-MS Method to Quantitate CVAA in Hemoglobin Adducts Joe V. Wooten CDC Confirmed
11:30 AM	LC-MS/MS Analysis of Urinary Excreted Pain Medications Offers Improved Patient Compliance, Detection of Diversion and Illicit Drug Use Amadeo Pesce Millennium Laboratories Confirmed	Technical and Other Barriers Impeding the Expansion of the Clinical Plasma Proteome Leigh Anderson Plasma Proteome Institute Confirmed	Retropective Analysis of Hydrogen Cyanide Exposure via Mass Spectral Detection of a Unique Cys-SCN Human Serum Albumin Adduct Michael Fasco NY State Dept of Health Confirmed
	Poster Splash	Poster Splash Proteomics 2	Poster Splash
12:00 PM	1. Therapeutic Drug Monitoring of Busulfan by Liquid Chromatography-Electrospray-Tandem Mass Spectrometry (HPLC-ESI-MS/MS) Marion L. Snyder Brigham and Womens Hospital Confirmed 11. Development of a Multiplexed SRM Assay for Osteoarthritis Biomarkers Bryan Krastins Thermo Fisher Scientific Confirmed 21. The CDC Testosterone Standardization Effort Julianne Cook Botelho CDC Confirmed
12:06 PM	3. LC-MS/MS Reveals High False Positive Rate of Ethylglucuronide Immunoassay in a Pain Management Population Bridgit Crews Millennium Laboratories Confirmed 13. Methionine Oxidation of the A and C Apolipoproteins in Patients with Type 2 Diabetes Matthew R. Schaab Arizona State University Confirmed 23. Phytoestrogen Biomonitoring: An Extractionless LC-MS/MS Method for Measuring Urinary Isoflavones and Lignans Using Atmospheric Pressure Photoionization (APPI) Daniel L. Parker CDC Confirmed
12:12 PM	5. Deuterium Labelled Sirolimus: Synthesis and Assessment as Internal Standard in a New LC/MS/MS Method Kun-Young Sohn McMaster University Confirmed 15. Proteomic Identification of Coccidioidal Antigens from Lung Fluid of Infected Mice: Applications in Diagnostic Test Development Forrest S.E. Helfrich University of Arizona Confirmed 25. Arsenic Speciation in Urine: the Minnesota Children’s Arsenic Study Betsy Edhlund Minnesota Department of Health Confirmed
12:18 PM	7. Discovery, Verification and Multi-technique Assay of a New Serum Protein Biomarker of Ovarian Cancer Tumor Burden CANCELED Paul Russo George Mason University Confirmed 17. Detection of Beta Amyloid Fragments by Mass Spectrometry from Biological Samples and Differential Expression of these Fragments in Alzheimer’s Patients Fiona Plows Bio-Rad Laboratories Confirmed 27. A Novel, MS/MS Assay to Detect Hexosaminidase Activity in Tay-Sachs and Sandhoff Disease Using Dried Blood Spots Michele Etter University of Saskatchewan Confirmed
12:24 PM	9. DESI-MS/MS of Xenobiotics in Dried Biological Fluids on Filter Paper and Microextraction Devices: Implications for TDM and other Clinical Applications Justin M. Wiseman Prosolia Confirmed 19. Understanding Cross-Lab Reproducibility for SRM-based Mass Spectrometry Clinical Assays Amol Prakash Thermo Fisher Scientific Confirmed 29. Advanced Applications of the Triple Quadropole/Linear Ion Trap Mass Spectrometer and High Performance Liquid Chromatography for Identification and Quantitative Measurement of HIV Prophylactic Drug Metabolites in Macaque Blood and Tissue Zsuzsanna Kuklenyik CDC Confirmed
12:30 PM	LUNCH (provided) Pick it up before attending a workshop. LUNCH & LEARN: Industrial Workshops 12:45 - 1:45 PM Current Trends and the Future Direction of Tandem MS in Clinical Research and Targeted Protein Quantification AB SCIEX Track 1 Bayview I/II High Throughput Accurate Determination of Pb, Cd, As and Hg in Whole Blood Using Collision/Reaction Cell ICP-MS Agilent Track 2 Mission II/III Harmonization of LC/MS Tests in the Clinical Laboratory – A Vendor’s Perspective Waters Track 3 Bayview I Introducing Ionics 3Q Molecular Analyzer, the New Generation Triple Quadrupole Mass Spectrometer Ionics Track 4 Mission I EXHIBITS & POSTERS in the Exhibit Hall
	Vitamin D Chair: Ravinder Singh Track 1	Microbes and Infectious Disease Chair: Steve Drake Track 2	Newborn Screening Chair: Victor De Jesus Track 3
3:00 PM	Large-Scale 25OHD Testing Ravinder Singh Mayo Clinic Confirmed	Clinical Perspective of Microbial Identification in the Clinical Laboratory Brad Cookson University of Washington Confirmed	Evaluation of a UPLC-MS Metabolic Profiling Platform for the Detection and Diagnosis of Inborn Errors of Metabolism Elizabeth Want Imperial College London Confirmed
3:30 PM	Pitfalls in the Implementation of 25OH Vitamin D Assays by LC-MS Darryl Erik Palmer-Toy Kaiser Permanente Confirmed	Microorganism Identification by MALDI in a Clinical Lab Steve Drake National Institutes of Health Confirmed	Newborn Screening for Lysosomal Storage Disorders Joseph Orsini NY State Dept of Health Confirmed
4:00 PM	Development of Reference Materials to Support Accuracy in Measurement of 25-Hydroxyvitamin D CANCELLED: FILL w/ PANEL DISCUSSION Karen Phinney NIST Confirmed	Mass Spectrometry in Biopharmaceutical Pathogen Detection Richard Ill Amgen Confirmed	An Effective Strategy to Characterize Acylglycines in Urine using UPLC MS/MS Avalyn Lewis University of Alberta Confirmed
	Poster Splash Vitamin D	Poster Splash Microbiology and Tissue	Poster Splash Various
4:30 PM	2. The Analysis of 25-hydroxyvitamin D in Serum Using Semi-Automated Solid Phase Extraction and LC/MS/MS Donald Mason Waters Confirmed 12. Analytical Methods for Capsid Serotype Identification of Gene Therapy Vectors Kim Van Vliet University of Florida, Dept of Medicine Confirmed 22. A Rapid and Fully-Automated Method for the Quantitation of Tricyclic Antidepressants in Serum using Turbulent Flow Liquid Chromatography-Tandem Mass Spectrometry Autumn Breaud Johns Hopkins University Confirmed
04:36 PM	4. Enhancing Limits of Detection of Derivatized Vitamin D3 and its Metabolites using ESI-LC/MS/MS and Derivatisation Subhakar Dey Applied Biosystems Confirmed 14. Automated Detection of Mixed Cultures of Microorganisms Using MALDI-TOF Mass Spectrometry Markus Kostrzewa Bruker Daltonik Confirmed 24. Comparison of Free Testosterone by Equilibrium Dialysis-LC-MS/MS versus LC-MS/MS Followed by Mathematical Modeling Evrim Erdogan ARUP Confirmed
04:42 PM	6. High Throughput LC/MS/MS-based Quantification of 25-hydroxy Vitamin D2, 25-hydroxy Vitamin D3 and 3-epi-25 hydroxy Vitamin D3 in Dried Blood Spots: Aiming to Cover Entire Clinical Practice Human Population Range, Infants to Elderly Suma Ramagiri MDS Analytical Technologies Confirmed 16. MALDI Mass Spectrometry-based Molecular Phenotyping of Neuroglia for Prediction in Mammalian Brain Tissue Jorg Hanrieder Uppsala University Confirmed 26. A Fully-Automated Two Dimensional Liquid Chromatography Isotope Dilution Mass Spectrometry Method for Quantification of Serum Creatinine Robert Harlan Johns Hopkins University Confirmed
04:48 PM	8. Rapid Analysis of 25OH Vitamin D by LC-MS/MS and Association of Vitamin D and PTH in Healthy Adults Mark Kushnir ARUP Confirmed 18. PCR and Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) for Identifying Viral Respiratory Infections Robert Lovari Ibis Biosciences Confirmed 28. Determination of Serum 25-Hydroxyvitamin D Status in County Hospital Patients Using a Robust and Rapid LC-MS/MS Assay Deborah French UCSF Confirmed
04:54 PM	10. A Sensitive and Robust LC-MSMS Assay for Vitamin D2 and D3 Using Human Serum Calibrators Alex Cherkasskiy PerkinElmer Confirmed 20. Rapid Microorganism Identification by MALDI Mass Spectrometry Protein Biomarker of Ovarian Cancer Tumor Burden Fan Xiang (replacing Scott Kuzdzal) Shimadzu Confirmed 30. A Fast and Sensitive Method for the Analysis of Serum 25-hydroxyvitamin D2 and D3 using UPLC-MS/MS Yun Wei University of Alberta Hospital Confirmed
5:00 PM	RECEPTION IN EXHIBIT HALL / POSTERS
7:30 PM	Tuesday Evening Workshops MSACL 2011 Organizing Committee Chair: David Herold Palm I/II Metabolomics and Inborn Errors Chair: Gary Siuzdak Track 2 Regulations and Standards Chair: Hubert Vesper Track 4 Proteins, Proteomics and Disease Markers Chair: Andy Hoofnagle Track 3 Small Molecule, Tox, Environmental Chair: Russ Grant Track 1 TBA
8:30 PM	Hospitality Suite Palm I/II

	Wednesday Feb 10
7:00 AM	BREAKFAST (provided)
	Sample Preparation Strategies Chair: Jeremy Norris Track 1	Protein and Metabolite Analysis from Tissue Chair: Gary Patti Track 2	Inorganic Analytes Chair: Martin Shafer Track 3
8:00 AM	Preparative Electrophoresis of Clinical Samples for Analysis by Mass Spectrometry Jeremy Norris Protein Discovery Confirmed	Mapping Dysregulated Metabolic Pathways in Cancer by Integrated Proteomics and Metabolomics Daniel Nomura The Scripps Research Institute Confirmed	Elemental Mercury Exposure Event, Carson City, Nevada Elemental Mercury Analysis of Whole Blood and Urine in Children and Adults by Inductively Coupled Plasma/ Mass Spectrometry David R. Quilici Nevada State Public Health Lab Confirmed
8:30 AM	Automated In-Line SPE/HPLC/MS/MS Kim Gamble MicroLiter Confirmed	Tissue Imaging by Nanostructure-initiator Mass Spectrometry (NIMS): from Pharmacokinetics to Disease Models Oscar Yanes The Scripps Research Institute Confirmed	Quantification of Perchlorate and Related Anions in Human Matrices using IC-MS/MS Benjamin Blount CDC Confirmed
9:00 AM	Thoughts on Mass Spectrometric Immunoassays Randall Nelson Arizona State University Confirmed	Metabolomics of Aging Gary Siuzdak The Scripps Research Institute Confirmed	High-Precision Isotope Ratio Analysis with Sector-based Single-Collector ICP-MS: Clinical Applications of Ca and Fe Stable Isotope Systems Martin Shafer University of Wisconsin-Madison Confirmed
9:30 AM	Screening for Unlimited Number of Drugs in Urine Samples Using On Line Turbo Flow Sample Preparation Technology and Ultra High Resolution Mass Spectrometry Marta Kozak Thermo Scientific Confirmed	Clinical Diagnosis of Amyloidosis on Paraffin Embedded Tissue by MS-based Proteomic Analysis Ahmet Dogan Mayo Clinic Confirmed	High Throughput Blood Metals Panel using ICP-MS Ryszard Gajek California Dept of Public Health Confirmed
10:00 AM	COFFEE BREAK
	Accelerator MS Chair: Darren Hillegonds Track 1	Targeted Proteomics Chair: Leigh Anderson Track 2	Environmental Biomonitoring Chair: Carin Huset Track 3
10:30 AM	BioAMS: Past, Present and Future Ken Turteltaub Lawrence Livermore National Laboratory Confirmed	Protein/Peptide LC-MS/MS Assay Validation and Quantitation - What's the Diagnosis? Nigel Clarke Quest Diagnostics Confirmed	Human Biomonitoring of Perfluorochemicals in Communities with Contaminated Drinking Water in the East Metro of St. Paul, Minnesota Carin Huset Minnesota Dept of Health Confirmed
11:00 AM	Quantifying Clinical Markers of Disease and Therapy with 14C-AMS John S. Vogel Vitalea Science Confirmed	Simultaneous Phenotyping and Quantitation of α-1-Antitrypsin by LC-MS/MS Bob Bergen Mayo Proteomics Research Center Confirmed	Use of Newborn Screening Blood Spots for Measurement of Neo-natal Exposure Status to Environmental Chemicals Kenneth Aldous NY State Dept of Health Confirmed
11:30 AM	Design of a Phase 0 Microdosing Clinical Trial to Determine Chemoresistance using Accelerator Mass Spectrometry Chong-xian Pan University of California, Davis Confirmed	A High Throughput Mass Spectrometric Immunoassay for Parathyroid Hormone Microheterogeneity in Renal Failure Populations: Identification of PTH1-84, C-PTH Variants, and C-PTH C-terminally Truncated Variants Paul Oran Arizona State University Confirmed	High Resolution GC/MS Measurement of Triclosan and Pentachlorophenol from Historic Cohorts of California Women (1960s, 1980s, 2000s) June-Soo Park California EPA Confirmed
12:00 PM	LC-MS/MS and AMS Analysis Together is Greater than the Sum of their Parts Graham Lappin Xceleron Confirmed	Candidate Biomarker Quantitation in Plasma Using MRM-based Assays and Observations from Inter-Laboratory Studies Susan Abbatiello Broad Institute Confirmed	HPLC-MS/MS Method Development for the Determination of 3,5,6-Trichloropyridinol (TCPy) and 3-Phenoxy Benzoic Acid (3-PBA) in Human Urine Paramjit Behniwal California Dept of Public Health Confirmed
12:30 PM	LUNCH (provided)
	New Advances Chair: Rob Fitzgerald Track 1	Discovery Metabolomics Chair: Shawn Ritchie Track 2	Emergency Response Chair: William Draper Track 3
2:00 PM	Tissue Proteomics and Tandem Mass Spectrometry Reveal Differential and Compartment-Specific Expression of the Homologs Transgelin and Transgelin-2 in Lung Adenocarcinoma and Its Stroma Michael Roehrl Harvard Medical School Confirmed	Ten Years of Discovery Metabolomics: Concepts, Challenges and Opportunities Shawn Ritchie Phenomenome Confirmed	Determination of the Cyanide Metabolite, L-2-Amino-2-Thiazoline-4R-Carboxylic Acid (L-ATCA), in Human Urine by Automated Solid Phase Extraction and Isotope Dilution LC-MS-MS William M. Draper California Dept of Public Health Confirmed
2:30 PM	Translating Bacterial Metabolic Exchange with Imaging Mass Spectrometry Pieter C. Dorrestein University of California, San Diego Confirmed	Clinical Applications of Targeted Metabolite Analysis Using Mass Spectrometry Sascha Dammeier Biocrates Life Sciences Confirmed	Evolution of Clinical Chemical Emergency Response Robert Kobelski CDC Confirmed
3:00 PM	Rapid Identification of Bacteria and Candida from Blood Culture Bottles using the Ibis Sterile Fluid Bacterial Assay Erin M. Johnson University of Arizona Confirmed	Derivatization for Lipidomics: Analysis of Free Fatty Acids, Neutral and Polar Lipids by UHPLC-FTMS Without Prior Fractionation Ivana Bobeldijk TNO Quality of Life Confirmed	Quantitation of Alpha-Amanitin, T-2, HT-2, DAS and DON in Human Urine Rudolph Johnson CDC Confirmed
3:30 PM	Qualitative and Quantitative Assessment of B-type Natriuretic Peptide (BNP) in Patients with Chronic Heart Failure Using Sensitive MSIA Technology Eric E. Niederkofler Intrinsic Bioprobes Confirmed	A Combined Mass Spectrometry and Nuclear Magnetic Resonance Metabolomics Approach to Detect Breast Cancer Recurrence Daniel Raftery Purdue University Confirmed	Diagnosis of Early Anthrax Infection and the Quantification of Anthrax Toxins using Mass Spectrometry John R. Barr CDC Confirmed
4:00 PM	Hospitality Suite Hyatt Penthouse

Poster Presentations

POSTERS: Monday Feb 8
Exhibit Hall: 2:00-3:00 PM
Includes All PosterSplashes Presented from the Podium Between 12:00-12:30PM
	31. Measurement of Steroid Hormones in Human Serum Samples by LC-MS/MS Jason Cournoyer PerkinElmer Confirmed	33. Rapid High-Throughput LC/MS/MS Assays for 13 Commonly Prescribed Pain Management Drugs and 11 Drugs of Abuse (Expanded SAMHSA) from Urine with Cleanup Using Solid Phase Extraction (SPE) Michael Campognone Phenomenex Confirmed	35. Setting-Up a LC-MS/MS Method Coupled to an Automatic On-Line Sample Clean-Up for a Multiplex Lysosomal Storage Disorders Screening Bruno Casetta AB Sciex Confirmed
	37. Discovery of Mammalian Cardenolide Hormone (MCH-518) using FT-ICR-MS and Tandem Mass Spectrometry Mohammad Al-Ghoul University of Louisville Confirmed	39. The CSF Metabolome as Primary Biomarker Compartment for CNS Disorders Leon Coulier TNO Quality of Life Confirmed	41. Determination of Urinary Metanephrine and Normetanephrine by LC-MS/MS Following Solid Phase Extraction Zlata D Clark ARUP Confirmed
	43. LC-MSMS Method Development for Steroid Analysis at Low Detection Limits Hua-fen Liu AB SCIEX Confirmed	45. Optimizing the Peptide Quantitation Workflow from Biomarker Discovery to Validation Christine A Miller Agilent Technologies Confirmed	47. Drug Testing in Expired Air? Detection of Amphetamine and Methamphetamine in Drug Addicts Olof Beck Karolinska Institutet Confirmed
	49. Rapid Detection and Identification of Tick-Borne Pathogens Directly from Blood using PCR and Electrospray Ionization Mass Spectrometry Mark Eshoo Ibis Biosciences Confirmed	TBD	TBA
Exhibit Hall: 6:30-7:30 PM
Includes All PosterSplashes Presented from the Podium Between 4:30-5:00PM
	32. A Strategy for Integrating the Inborn Errors Metabolism Screening with the Congenital Adrenal Hyperplasia Screening in a single LC-MS/MS measurement Bruno Casetta AB SCIEX Confirmed	34. A High Throughput Mass Spectrometric Immunoassay for RANTES in Diabetic Populations: An Abundance of RANTES Microheterogeneity Identified Paul E. Oran Arizona State University Confirmed	36. Proteomic Biomarkers of Traumatic Brain Injury Rajeswari Lakshmanan UCLA Confirmed
	38. Clinical Diagnosis of Amyloidosis in Fat Aspiration Biopsies Using Mass Spectrometry-Based Proteomics Ahmet Dogan Mayo Clinic Confirmed	40. Measurement of 5.9 kDa Fragment of Fibrinogen Alpha Chain C-terminal(FIC 5.9) by MALDI-TOF MS with Stable-Isotope Labeled Standard in Patients with Broad Spectrum Liver Diseases Fumio Nomura Chiba University Confirmed	42. Design of a Selected Reaction Monitoring Mass Spectrometric Immunoassay Responsive to Human Parathyroid Hormone and Related Variants Mary F Lopez ThermoFisher Scientific Confirmed
	44. Quantification of Steroids and 25-OH Vitamin D3 in Dried Blood Spots and Serum Using Liquid Chromatography Tandem Mass Spectrometry Hua-fen Liu AB SCIEX Confirmed	46. Testosterone Analysis Using Derivatization Chemistry and LC/MS/MS Michal Weinstock Applied Biosystems Confirmed	48. LC/MS/MS Tamoxifen Metabolite Profiling for Clinical Pharmacogenetic Testing Chunli Yu Mount Sinai School of Medicine Confirmed
	50. Clinical Application of Stable and Radioactive Isotope Ratio Mass Spectrometry Darren J. Hillegonds Lawrence Livermore National Laboratory Confirmed	TBD	TBA

POSTERS: Tuesday Feb 9
Exhibit Hall: 2:00-3:00 PM
Includes All PosterSplashes Presented from the Podium Between 12:00-12:30PM
	31. Quantification of 17-Hydroxyprogesterone from Dried Blood Spots using Liquid Chromatography Tandem Mass Spectrometry Donald Mason Waters Confirmed	33. Mass Spectrometry-based Quantification and Characterization of Urine Albumin Ashley S. Beasley NIST Confirmed	35. Simultaneous Quantitative Analysis of 13 Anti-Retroviral Drugs in Human Serum using HPLC Triple Quadrupole Mass Spectrometry Susan C. Leonard Applied Biosystems Confirmed
	37. Complex Peptide Mixture Fractionation via Parallel Isoelectric Focusing for Direct LC-MS/MS Analysis Jim Dasch Protein Forest Confirmed	39. Analysis of Multiple Protein Marker Panels: Optimizing Sensitivity and Selectivity Michael Athanas VAST Scientific Confirmed	41. Method Comparison of Immunosuppressant Quantitation: Abbott ARCHITECT versus LC-MS/MS Jonathan Hoyne Mayo Clinic Confirmed
	43. Evaluation of a Method for the Analysis of Hydroxocobalamin and Cyanocobalamin in Plasma by Liquid Chromatography Mass Spectrometry (LC/MS/MS) Sandra Valtier Lackland AFB Confirmed	45. Newborn Screening by MS/MS using Integrated Ion Peak Height- A Comparative Study with Spectrum Intensity MP George Agilent Confirmed	47. A Rapid Analysis of Testosterone in Serum using Two Dimensional HPLC System M P George Agilent Confirmed
	49. Development and Application of a Pesticide Library for the Identification and Confirmation Analysis in Various Sample Matrices by LC/MS/MS Andre Schreiber Applied Biosystems Confirmed	TBA	TBA
Exhibit Hall: 6:30-7:30 PM
Includes All PosterSplashes Presented from the Podium Between 4:30-5:00PM
	32. Increased Throughput of Vitamin D Analysis using a Multiple Parallel LC-MS system Robert Ellis MDS Analytical Technologies Confirmed	34. Quantitation of Methylmalonic Acid in Plasma using Hydrophilic Interaction Liquid Chromatography on a Zwitterionic Stationary Phase and Negative Electrospray MS Patrik Appelblad Merck SeQuant Confirmed	36. Accelerated LC/MS/MS for the Quantitation and Identification of Pesticides, Pharmaceuticals, and Personal Care Products in Environmental Samples Andre Schreiber Applied Biosystems Confirmed
	38. Discovery of Mitochondrial Protein Biomarkers of Atrial Fibrillation using Unique Human Tissue Samples CANCELED Maryam Goudarzi George Mason University Confirmed	40. A New UPLC-MS/MS Method for the Determination of Urinary Globotriaosylceramide (Gb3, GL3 or CTH) Sabrina Forni Baylor Research Institute Confirmed	42. Immunosuppresant Solution Reference Standards Uma Sreenivasan Cerilliant Confirmed
	44. Method Development to Measure Phthalate in Human Urine Specimen using LC-MS/MS Rana Zahedi California Department of Public Health Confirmed	46. Extraction of Plasma Free Metanephrine (MN) and Normetanephrine (NMN) Using Strata™-X-CW and LC/MS/MS on Luna® HILIC Philip J. Koerner Phenomenex Confirmed	48. Automated Picoliter to Nanoliter Sample Deposition for Mass Spectrometry Glen Donald SonoPlot Confirmed
	50. Ion Trap and Q-TOF MS and MS/MS for Clinical Toxicology and other Clinical Applicaitons Gary Kruppa Bruker Daltonics	TBA	TBA

Exhibits

Exhibit Hall Hours Sun 5:00-7:30 PM Reception Mon 12:30-3:00 PM Lunch Mon 5:30-7:30 PM Reception Tue 12:30-3:00 PM Lunch Tue 5:30-7:30 PM Reception
	AB Sciex Booth 1	Agilent Technologies Booth 9	Phenomenex Booth 17
	Cerilliant Booth 2	Abbott Booth 10	Peak Scientific Booth 18
	BIOCRATES Life Sciences Booth 3	Indigo Biosystems Booth 11	MicroLiter Analytical Supplies Booth 19
	Thermo Scientific Booth 4	MicroSolv Booth 12	Tecan Booth 20
	Thermo Scientific Booth 5	Virgin Instr & Intrinsic Bioprobes Booth 13 (Shared)	Ionics Booth 21
	Quest Diagnostics Booth 6	Cambridge Isotope Labs Booth 14	Michrom Bioresources Booth 22
	Waters Booth 7	PerkinElmer Booth 15	Bruker Daltonics Booth 23
	Phenomenome Discoveries Booth 8	IsoSciences Booth 16

Exhibit Hall Diagram