54. MALDI and LCMS Identifications of Protein and ICP-MS Identification of Metal Biomarkers of Ionizing Radiation
Poster: Mon 6:30-7:30PM
Paul H Pevsner
University of Missouri School of Medicine
View Long Abstract
The goal of this project was the identification of dose-related protein biomarkers of ionizing radiation (IR), specifically, biomarkers of the 2 Gy threshold dose for radiation sickness, and similar markers of the metal elements: iron, copper, zinc, phosphorous, and calcium. Mass spectrometry, both imaging MALDI and LCMS were the discovery tools used for proteins. Ion conductance plasma mass spectrometry (ICP-MS) was the discovery tool used for the metal elements.