| 51. Reducing the Need for Technical Replicates - Implementation of Peptide QC Standards |
| Poster: Tue 2:00-3:00PM |
Scott Peterman
ThermoFisher Scientific |
| View Long Abstract |
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| The use of peptide standards for protein quantitation has many advantages. In addition to QC markers for LC-MS performance analysis, the standards can provide a measure of variability analysis reducing the need for multiple technical replicates to establish analytical precision. We present a study to compare the analytical precision of differential quantitation for a series of targeted proteins across 12 samples based on increasing number of technical replicates with and without normalization of a set of peptide QC standards based on high resolution/accurate mass detection from a benchtop orbitrap. |
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| Email: scott.peterman@thermofisher.com |
