| In addition to detection of biomarkers of congenital disorders, dried blood spots (DBS) can be used in determination of exposure to toxic environmental chemicals in newborn babies. A pilot study was conducted for the determination of some polar and moderately polar environmental toxicants, including perfluorinated compounds, bisphenol A, polychlorinated biphenyls, polybrominated biphenyl ethers, and organochlorine pesticides, in DBS. The result clearly suggests that DBS containing approximately 40µL of blood is adequate for the analysis of these chemicals. Further studies are on-going to improve and validate the analytical methods for the measurement of a range of environmental toxicants in DBS samples. |
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