MSACL 

Simultaneous Multi-Targeted and Unknown Screening of Urine Samples by LC-MS/MS with Automated Library Searching for Compound Identification
Wed 8:30 AM - Track 1: Toxicology
Michael Jarvis
AB Sciex
View Long Abstract
Toxicology screening is generally divided into two categories: multi-targeted screening (MTS) and general unknown screening (GUS). Each approach has both advantages and disadvantages. In this work, a new LC-MS/MS methodology will be presented which combines both MTS and GUS analyses, in a single run. An AB SCIEX QTRAP hybrid tandem mass spectrometer-linear ion trip is used in order to acquire both quantitative (MRM) and qualitative (linear ion trap full-scan MS/MS) information. The MS/MS spectra are automatically submitted for library searching for confirmation of compound IDs.
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