Krista Pratico (Presenter)
UCSD Center for Advanced Laboratory Medicine
Bio: Krista Pratico works as a clinical lab scientist in the clinical toxicology lab at the Center for Advanced Laboratory Medicine, UC San Diego Health System. Her research interests include development of IT tools to improve LC-MSMS workflows and interfacing, and LC-MSMS method development.
Authorship: Krista Pratico
UCSD Center for Advanced Laboratory Medicine, 10300 Campus Point Drive, San Diego, CA 92121
| Short Abstract Mass spectral data review and result entry can be a time consuming and sometimes erroneous process leading to unfavorable patient outcomes. While commercial data analysis software is available, vendor software can be used to automate some aspects of data review and calculate meta-data to generate flagging for outliers needing additional review. We describe the development and validation of semi-automated workflows using vendor software in conjunction with an LIS-based rules engine. An alternative approach using a rules engine integrated with middleware will also be described. Both yield significant productivity and decreased turn-around-time in high to moderate volume LC-MS laboratories. |
Long Abstract
Mass spectral data review and result entry can be a time consuming and sometimes erroneous process leading to unfavorable patient outcomes. While commercial data analysis software is available, vendor software can be used to automate some aspects of data review and calculate meta-data to generate flagging for outliers needing additional review. We describe the development and validation of semi-automated workflows using vendor software in conjunction with an LIS-based rules engine. An alternative approach using a rules engine integrated with middleware will also be described. Both yield significant productivity and decreased turn-around-time in high to moderate volume LC-MS laboratories.
References & Acknowledgements:
• Judy Stone | UCSD Toxicology/Mass Spectrometry Laboratory
• Jonathan Agustin | TPMG Kaiser Regional Laboratory
• Tony DaSilva | TPMG Kaiser Regional Laboratory
• Shamim Haider | AB Sciex
• Dave Lavorato | AB Sciex
• Chris Borton | AB Sciex
• Friedrich Brunzema | AB Sciex
• Bret Pehrson | AB Sciex
• John Gibbons | AB Sciex
• Michael Jarvis | AB Sciex
• Janna Anichina | AB Sciex
• Mark George | Waters Co.
• Patrick Kelly | Data Innovations
• Don Jarvis | Data Innovations
• David Pope | UC San Diego LIS group
• Melodie Bayongan | UC San Diego LIS group
• David Buchanan | UC San Diego LIS group
• Mike Vogelsberg | SCC SOFT Computer
• Krystyna Hagmajer | SCC SOFT Computer
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IP Royalty: no
| Planning to mention or discuss specific products or technology of the company(ies) listed above: | no |