MSACL 2016 US Abstract

Part 2: Introduction to Clinical Proteomics

Timothy Collier (Presenter)
Cleveland HeartLab Inc

Bio: Ph.D. - 2010, NC State University under David Muddiman in Quantitative Proteomics Post-Doc - 2010-2013, Washington University in St. Louis under Ron Bose using quantitative mass proteomics to characterize signal dynamics of drug resistant breast cancers. Currently Research and Development Scientist at Cleveland Heartlab under Cory Bystrom developing new quantitative proteomic assays of diagnostic or prognostic value in Cardiovascular Health.

Short Abstract

A mass spectrometer is more than a box with specimens going in and a numbers coming out. This part of the session will discuss a few of the most used types of mass spectrometers in the clinical laboratory and how they perform their measurements in the context of proteomic diagnostics. This includes: [1] Protein/Peptide ionization, [2] Guiding ions through the instrument, [3] Fragmentation (MS/MS), [4] Detection, and [5] Tools for Data Interpretation.

Long Abstract

A mass spectrometer is more than a box with specimens going in and a numbers coming out. This part of the session will discuss a few of the most used types of mass spectrometers in the clinical laboratory and how they perform their measurements in the context of proteomic diagnostics. This includes: [1] Protein/Peptide ionization, [2] Guiding ions through the instrument, [3] Fragmentation (MS/MS), [4] Detection, and [5] Tools for Data Interpretation.


References & Acknowledgements:


Financial Disclosure

DescriptionY/NSource
Grantsno
SalaryyesCleveland HeartLab, Inc.
Board Memberno
Stockno
Expensesno

IP Royalty: no

Planning to mention or discuss specific products or technology of the company(ies) listed above:

no