MSACL 2017 EU Abstract

Pragmatic HILIC for the Clinic

Brian Rappold (Presenter)
Essential Testing

Authorship: Brian Rappold
Essential Testing, LLC

Short Abstract

Hydrophilic-interaction-liquid chromatography (HILIC) is a separation technique orthogonal to the more commonly used reversed-phase chromatography. Reversed phase techniques are, in general, useful for non-polar compounds but poorly suited to the separation of highly polar compounds. HILIC techniques provide broad capabilities in polar separations, but the diagnostic LC-MS assays utilizing HILIC are infrequent, perhaps due to misunderstandings in the differences between HILIC and reversed-phase separations in regards to development and utility. This series will discuss development and practical fundamentals of the HILIC technique.

Long Abstract

References & Acknowledgements:

Financial Disclosure

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