Stefan Grebe (Presenter)
Mayo Clinic
Bio: Stefan Grebe, MD/PhD, is Professor of Laboratory Medicine & Pathology, College of Medicine Mayo Clinic. He obtained his doctoral degrees in his native country of Germany and trained in Internal Medicine and Endocrinology in Germany and New Zealand (FRACP 1994). He is also Board Certified in Clinical Chemistry (2006) and Molecular Diagnostics (2007). From 2002-2015 he was co-director of the Endocrine Laboratory (Department of Laboratory Medicine & Pathology, Mayo Clinic, Rochester, MN). Since mid-2015 he is a co-director of the Clinical Mass Spectrometry Laboratory at the Mayo Clinic He has 136 scientific publications (107 peer-reviewed, 17 book chapters, 12 other) and co-holds 3 patents. His interests are molecular diagnostics, tumor markers in endocrine tumors, and clinical applications of mass spectrometry, including peptide/protein measurements and metabolomics.
Authorship: Stefan K. G. Grebe, MD/PhD
Mayo Clinic, Rochester, Minnesota
| Short Abstract During the last two decades, mass spectrometry (MS) has revolutionized clinical testing of low molecular weight hormones. Due to superior specificity and lesser susceptibility to interferences, MS is now regarded the best testing method for steroids, biogenic amines, and most vitamins. The last decade has seen an extension of MS to the clinical measurement of peptide and protein hormones, while most recently, clinical laboratories have started to experiment with metabolomics MS applications. High resolution, accurate mass MS and antibody-mediated enrichment of the targeted analytes have been key facilitators of these more recent expansions of clinical MS. |
Long Abstract
References & Acknowledgements:
| Description | Y/N | Source |
| Grants | no | |
| Salary | no | |
| Board Member | no | |
| Stock | no | |
| Expenses | no |
IP Royalty: yes
IP Desc:Vitamin D testing by mass spectrometry
| Planning to mention or discuss specific products or technology of the company(ies) listed above: | no |