Sankha (Bobby) Basu (Presenter)
Brigham and Women's Hospital
Authorship: Sankha (Bobby) Basu, Nathalie Agar
Harvard Medical School, Brigham and Women's Hospital and Dana-Farber Cancer Institute
| Short Abstract Mass spectrometry provides multiple options for the direct characterization of tissue to support surgical decision-making, and provides significant insight in the development of drugs targeting tumors of the central nervous system (CNS). Using an array of mass spectrometry (MS) applications, we rapidly analyze specific tumor markers such as metabolites, fatty acids, lipids, and proteins from surgical tissue for surgical guidance and rapid diagnosis. Using similar clinical protocols, we visualize drug and metabolites penetration in brain tumor tissue and correlate with tumor heterogeneity and response to support drug development. |
Long Abstract
Mass spectrometry provides multiple options for the direct characterization of tissue to support surgical decision-making, and provides significant insight in the development of drugs targeting tumors of the central nervous system (CNS). Using an array of mass spectrometry (MS) applications, we rapidly analyze specific tumor markers such as metabolites, fatty acids, lipids, and proteins from surgical tissue for surgical guidance and rapid diagnosis. Using similar clinical protocols, we visualize drug and metabolites penetration in brain tumor tissue and correlate with tumor heterogeneity and response to support drug development.
References & Acknowledgements:
| Description | Y/N | Source |
| Grants | no | |
| Salary | yes | Pfizer, Bayesian Dx |
| Board Member | yes | Massachusetts Department of Public Health, Biomonitoring |
| Stock | no | |
| Expenses | no |
IP Royalty: no
| Planning to mention or discuss specific products or technology of the company(ies) listed above: | no |