MSACL 2017 US Abstract

Clinical Mass Spectrometry: A Gold Standard in Routine Applications

Alicia Hutcherson Wright (Presenter)
Providence Health & Services

Bio: Alicia Hutcherson Wright is currently a Medical Technologist in Clinical Toxicology at the Providence Health & Services Regional Laboratory, Oregon. She received her MS in Clinical Laboratory Science in 2009 from Virginia Commonwealth University with a focused concentration in Clinical Chemistry. She has since been primarily involved with method development and validation, laboratory operations, and advanced staff training in LC-MS/MS-based clinical applications.

Authorship: Alicia Hutcherson Wright, Alec Saitman
Providence Health & Services, Portland, OR

Short Abstract

Over the past few years, clinical laboratories have been increasingly adopting liquid chromatography with tandem mass spectral detection (LC-MS/MS) for a myriad of applications. With the increase in routine utilization, there may still stand the question of what exactly makes this technology appealing for clinical use? This presentation will describe several benefits to implementing this valuable ‘gold standard’ technique in routine applications.

Long Abstract

Over the past few years, clinical laboratories have been increasingly adopting liquid chromatography with tandem mass spectral detection (LC-MS/MS) for a myriad of applications. With the increase in routine utilization, there may still stand the question of what exactly makes this technology appealing for clinical use?

This presentation will describe how the inherent sensitivity and selectivity of LC-MS/MS contribute to regarding it as a 'gold standard' method for analytical measurements, and is a driving force behind the rapid growth in clinical applications. It will also compare and contrast performance between LC-MS/MS and other analytical methods, and illustrate how it provides improved outcomes. It will also highlight additional benefits of implementing and utilizing LC-MS/MS technology in the routine clinical laboratory.


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