MSACL 2018 US Abstract


A New Approach to Genome Editing

Alexis Komor (Presenter)
University of California, San Diego

Short Abstract

The CRISPR-Cas9 RNA-guided DNA endonuclease has contributed to an explosion of advances in the life sciences that have grown from the ability to edit genomes within living cells. Here I describe the development of base editing, a new approach to genome editing that enables the direct, irreversible conversion of one target DNA base into another in a programmable manner, without requiring double-stranded DNA backbone cleavage or a donor template. Base editing is one of many recent developments in the genome editing field that advances both the scope and effectiveness of genome editing.

Long Abstract

References & Acknowledgements:

Financial Disclosure

Board Memberno

IP Royalty: no

Planning to mention or discuss specific products or technology of the company(ies) listed above: