MSACL 2018 EU Abstract

Self-Classified Topic Area(s): Small Molecules

The Singapore Lipidomics Incubator: A Model for Engagement and Translation

Anne K Bendt (1), Tze Ping Loh (2) and Markus R Wenk (1,3)
(1) Singapore Lipidomics Incubator (SLING) at the Life Sciences Institute, National University of Singapore; (2) Department of Laboratory Medicine, National University Hospital, Singapore; (3) Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore

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Anne Bendt (Presenter)
National University of Singapore

Presenter Bio: MSc (Biol), U Greifswald/ Germany
PhD (Biochem), U Cologne/ Germany
PostDoc (mycobacterial lipidomics), U Singapore
Scientific Program Manager; since 2008
Associate Director of the Singapore Lipidomics Incubator; since 2015
Principal Investigator at the Life Sciences Institute/Singapore; since 2015

I am a Principal Investigator in the Singapore Lipidomics Incubator (SLING), anchored within the Life Sciences Institute of the National University of Singapore. In addition to my active research & translation role, I have also been serving as SLING’s Associate Director since 2015.
My main research interests include Lipidomics tools and their applications, especially for development of biomarkers and diagnostics; Infectious Diseases; Translation & Commercialization; Operations.
More info: https://www.lsi.nus.edu.sg/corp/research-programmes/sling/principal-investigators/anne-k-bendt/

Relevant Financial Disclosures (within past 24 months, reported on Apr 07, 2021)

No relevant financial relationship(s) to disclose.

Discussing Products? NO, presenter will NOT present educational content related to products/services of the ineligible company(ies) listed above.

Conflict mitigation NOT REQUIRED.

Abstract

We developed a model of engagement to clinically translate LC-MS/MS-based analytical protocols to measure metabolites (lipids, small molecules) in human plasma. By close interactions with data scientists, clinicians and laboratory medicine, we are translating some of our lab-based technology into assays suitable for clinical applications. A special focus lies in understanding natural variation and population reference values. Data from ongoing studies in multi-ethnic cohorts will be discussed.