MSACL 2018 EU Abstract

Self-Classified Topic Area(s): Metabolomics

New Insights in CE-MS-based Metabolomics

Nicolas Drouin, Julian Pezzati, Yoric Gagnebin, Victor Gonzalez-Ruiz, Julie Schappler, Serge Rudaz
School of Pharmaceutical Sciences, Unviersity of Geneva, Geneva, Switzerland

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Nicolas Drouin (Presenter)
University of Geneva

Presenter Bio: I recently defenced my PhD. During my thesis work I focused on sample preparation and separation of highly polar compounds using electroassisted method such as electromembrane extraction and capillary electrophoresis respectively. In this context, I developped a new approach for features identification in untargeted metabolomic with CE-MS. This innovative approach is based on the conversion of migration time scale into an effective mobility (µeff) scale of the data and an experimental µeff based library of more than 400 endogenous compounds.

Relevant Financial Disclosures (within past 24 months, reported on May 17, 2021)

Salary University of Geneva

Discussing Products? NO, presenter will NOT present educational content related to products/services of the ineligible company(ies) listed above.

Conflict mitigation NOT REQUIRED.

Abstract

During this study, we developed an original workflow for features identification in CE-MS. This innovative approach is based on the conversion of migration time scale into an effective mobility (µeff) scale of data acquired in standardized conditions and an experimental µeff based library of more than 400 endogenous compounds.
This method allowed lab-to-lab identification of features from cell cultures.