Defining Boundaries of Lipidomic Variations in Human Cohorts
Federico Torta, Sock Hwee Tan, Peter Benke, Bo Burla, Wai Ling Koh, Hyung Won Choi, Mark Chan, Markus R Wenk National University of Singapore, Singapore
Warning: Undefined variable $headshot in /var/www/html/view_abstract/view_abstract_in_program.php on line 704
Federico Torta (Presenter) National University of Singapore
Presenter Bio: My area of expertise covers structural biology, proteomics and lipidomics. I hold a PhD in Molecular Biology and Pathology and became a Research Assistant Professor at NUS in 2016.
My main interest has always been in basic research but more recently I have been increasingly involved in translational and clinical research in large cohorts, especially in the field of metabolic diseases. My research interests lie at the intersection between lipids and proteins and in developing new analytical methodologies in the field, such as Native Mass Spectrometry, a powerful tool that can be used to study molecular complexes in native conditions.
Relevant Financial Disclosures
(within past 24 months, reported on May 19, 2021)
No relevant financial relationship(s) to disclose.
Abstract
Advances in mass spectrometry-based lipidomics have greatly expanded our understanding of the extent and complexity of lipid dysregulation in disease conditions. Targeted lipidomics enables the sensitive measurement of several hundred individual lipid species in thousands of samples for each study. We present here population-based studies aimed at clarifying the variation of plasma lipid concentrations in healthy individuals and in patients affected by metabolic disorders, in both cross-sectional and longitudinal studies.
= Discovery stage.
= Translation stage.
= Clinically available.
