Self-Classified Topic Area(s): Practical Training > Various OTHER
From Kit to Clinic: How to Implement LC-MS/MS Kits in the Clinical Lab
Katharina Habler Institute of Laboratory Medicine, LMU University Hospital, LMU Munich, Germany
Katharina Habler (Presenter) LMU University Hospital, LMU Munich
Relevant Financial Disclosures
(within past 24 months, reported on Apr 09, 2026)
No relevant financial relationship(s) to disclose.
Abstract
This practical training focuses on the real-world implementation of LC-MS/MS kits in routine diagnostic laboratories. The course will cover critical pre-purchase questions to ask vendors, including system compatibility, existing users, validation status, and available (often unpublished) knowledge. Stop/Go decision points are addressed, helping laboratories evaluate implementation challenges, decide when additional vendor support is justified, and recognize when transitioning to an LDT approach may be more appropriate. The training also covers common troubleshooting challenges, such as limited transparency around mobile phases and columns, and discusses strategic use of kit components such as calibrators and quality controls. Using successful implementation examples, participants will learn which validation/verification experiments are required and how to apply practical tips and shortcuts beyond the kit instructions.
Take-home pearls:
By the end of this practical training, participants will be able to:
1) Ask the right vendor questions before committing to a kit and during implementation of the kit.
2) Identify Stop&Go points during implementation of the kit.
3) Select kit components flexibly and effectively.
4) Define which validation and verification experiments are essential.
= Discovery stage. (57.21%, 2026)
= Translation stage. (23.38%, 2026)
= Clinically available. (19.40%, 2026)
