= Emerging. More than 5 years before clinical availability. (19.79%)
= Expected to be clinically available in 1 to 4 years. (37.97%)
= Clinically available now. (42.25%)
MSACL 2022 : Crawford

MSACL 2022 Abstract

Self-Classified Topic Area(s): Practical Training

Podium Presentation in Bonzai on Thursday at 14:00 (Chair: TBA)

Working Smarter Not Harder on Sample Prep

Matthew Crawford
Labcorp

Matthew Crawford (Presenter)
Labcorp

Abstract

With a suite of sample preparation tools at one’s disposal, where does one start? Theory can certainly provide guidance, but practical considerations may a better north star for the clinical laboratory environment. Certain aspects, such as analytical measurement requirements based on defined clinical reference intervals, can be a quick adjudicator for the type of sample preparation needed (i.e. dilutive or concentration approach) but not prescribe the exact procedure. Other practical considerations within the laboratory can include; turnaround time, laboratory/personnel requirements, automation, environmental/health safety, and cost. If not taken into account, one can end up with a sample preparation protocol which is labor intensive and costly. Is that necessary? Can a method be more efficient from a cost and labor perspective and not sacrifice quality? Examples of such considerations and method development journey resulting in two possible sample prep protocols are compared and discussed herein. Goals are to arm one with pragmatic and practical considerations for method development of robust clinical methods along with design and interpretation of fundamental experiments required to provide confidence in sample prep methods.


Financial Disclosure

DescriptionY/NSource
Grantsno
SalaryyesLabCorp
Board Memberno
Stockyes LabCorp
ExpensesyesMSACL
IP Royaltyno

Planning to mention or discuss specific products or technology of the company(ies) listed above:

no