This session will provide an overview of urine drug testing and will cover immunoassay and mass spectrometry methodologies, limitations and advantages of testing methods, and clinical interpretation of test results. Clinical laboratories use a variety of urine drug testing algorithms, such as screening only, screening with reflex to confirmation and direct to definitive testing. While mass spectrometry-based drug testing methods reduce the number of false positive and false negative results, no test is perfect. Using a case-based approach, we’ll review the advantages and limitations of mass spectrometry in urine drug testing and will troubleshoot unexpected results together.
Take Home Pearls:
1. Describe the advantages and limitations of various urine drug testing algorithms
2. Identify sources of false positive and false negative results in urine drug testing.
3. Interpret mass spectrometry data and troubleshoot unexpected urine drug test results.