= Emerging. More than 5 years before clinical availability. (24.37%, 2023)
= Expected to be clinically available in 1 to 4 years. (39.50%, 2023)
= Clinically available now. (36.13%, 2023)
MSACL 2023 : Badea

MSACL 2023 Abstract

Self-Classified Topic Area(s): Practical Training

Podium Presentation in Colton on Thursday at 10:00 (Chair: TBA)

Practical Considerations for Sample Prep Selection: Where Sensitivity, Cost, and Turnaround Time Collide

Adina Badea
Brown University

Adina Badea, PhD, DABCC (Presenter)
Lifespan/Rhode Island Hospital & the Warren Alpert Medical School of Brown University

Presenter Bio: Dr. Adina Badea, PhD, DABCC, earned her BA in Chemistry from Wellesley College, and her PhD in Chemistry from the University of Illinois at Urbana-Champaign. She completed her clinical chemistry and toxicology fellowship at UCSF, where she worked under the supervision of Dr. Alan Wu and Dr. Kara Lynch on developing methods and finding new solutions to current challenges in clinical toxicology testing. Currently, she is Director of Toxicology at Rhode Island Hospital and Assistant Professor of Pathology and Laboratory Medicine at The Warren Alpert Medical School of Brown University, where she focuses on expanding the capabilities of the clinical toxicology lab using high resolution mass spectrometry. Her research interests include bringing state-of-the-art testing to the service of emergency medicine patients and to address public health crises with real-time comprehensive toxicology testing via collaborations with the local Poison Control Center and Department of Health.



With the increasing popularity of liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods in the clinical laboratory came a multitude of applications and, consequently, many options for sample preparation. Sample prep is an essential clean-up step prior to LC-MS/MS analysis that can improve the sensitivity and robustness of your method, as well as prolong the lifetime of your instrumentation and higher-end consumables. But which sample prep approach is the best for you? This session will give a brief overview of the principles of sample preparation, discuss key factors to consider when selecting a strategy for sample preparation, and offer practical advice and tips on developing a protocol that works for your laboratory.

Take Home Pearls:
1. Understand the basic principles of sample preparation.
2. List the main factors to consider when choosing a sample prep approach.
3. Develop a sample prep protocol that suits their specific application and laboratory setup.

Financial Disclosure

Board Memberno
IP Royaltyno

Planning to mention or discuss specific products or technology of the company(ies) listed above: