= Emerging. More than 5 years before clinical availability. (9.82%)
= Expected to be clinically available in 1 to 4 years. (12.95%)
= Clinically available now. (22.77%)
MSACL 2018 EU : Horro Pita

MSACL 2018 EU Abstract

Topic: Practical Training

Podium Presentation in the Ether on Thursday at 9:00 (Chair: Catarina Horro-Pita)

Where Did My Analyte Go? – coping with poor solubility and non-specific binding

Catarina Horro Pita (Presenter)
LGC, Drug Development Solutions

Presenter Bio(s): Dr Catarina Horro Pita possesses a BSc in Chemistry and Environmental Chemistry and a PhD in Synthetic Organic Chemistry. After concluding her PhD, she initiated her professional career as a Synthetic Chemist, prior to moving into Analytical Chemistry and Bioanalysis. She currently holds a position as a Principal Scientist in Drug Development Solutions at LGC, where she has been working for the past eleven years. During her time at LGC, she has worked both as a Study Director, which has given her extensive experience in managing GLP and GCP studies, and as a Technical Specialist, leading LC-MS/MS method development projects for the analysis of both xenobiotic compounds and small molecule biomarkers.

Authors: Catarina Horro Pita, Michael Wright
LGC, Drug Development Solutions

Abstract

Poor solubility and non-specific binding can be insidious problems that are often overlooked during method development. These issues can result in costly and time-consuming batch failures during validation and, more importantly, the generation of inaccurate results during sample analysis. This training will describe in detail these issues, illustrate case studies and conclude with a workshop, where the audience will be asked to review ‘troublesome’ methods and suggest possible solutions.


Financial Disclosure

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