This one hour teaching session regarding Internal Standards will be delivered in three 20 minute vignettes.
The first session will describe in detail the "What, Why and How" Internal standards should be used in isotope dilution LC-MS/MS assays.
The second session "But what about when?" will describe situations where Internal Standards fail criterion for use and how to correct deficiencies for effective LC-MS/MS assays.
The third session will describe the "Unique capabilities" afforded to analytical measurement when used as internal calibrators/pre-analytic correction tools and in method development (as surrogates for analytes).