= Emerging. More than 5 years before clinical availability. (9.82%)
= Expected to be clinically available in 1 to 4 years. (12.95%)
= Clinically available now. (22.77%)
MSACL 2018 EU : Torta

MSACL 2018 EU Abstract

Topic: Metabolomics

Podium Presentation in the Ether on Wednesday at 9:00 (Chair: Julijana Ivanisevic)

Defining Boundaries of Lipidomic Variations in Human Cohorts

Federico Torta (Presenter)
National University of Singapore

Presenter Bio(s): My area of expertise covers structural biology, proteomics and lipidomics. I hold a PhD in Molecular Biology and Pathology and became a Research Assistant Professor at NUS in 2016.
My main interest has always been in basic research but more recently I have been increasingly involved in translational and clinical research in large cohorts, especially in the field of metabolic diseases. My research interests lie at the intersection between lipids and proteins and in developing new analytical methodologies in the field, such as Native Mass Spectrometry, a powerful tool that can be used to study molecular complexes in native conditions.

Authors: Federico Torta, Sock Hwee Tan, Peter Benke, Bo Burla, Wai Ling Koh, Hyung Won Choi, Mark Chan, Markus R Wenk
National University of Singapore, Singapore

Abstract

Advances in mass spectrometry-based lipidomics have greatly expanded our understanding of the extent and complexity of lipid dysregulation in disease conditions. Targeted lipidomics enables the sensitive measurement of several hundred individual lipid species in thousands of samples for each study. We present here population-based studies aimed at clarifying the variation of plasma lipid concentrations in healthy individuals and in patients affected by metabolic disorders, in both cross-sectional and longitudinal studies.


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