MSACL 2022 : Gibson

MSACL 2022 Industry Workshop Presentation

*This Podium Presentation is occuring in the context of an Industry Workshop that starts at the time below. Its actual start time may be up to 40 minutes later, depending on order of presentation if there are multiple presentations planned by the workshop host.

Workshop Host:Thermo Fisher Scientific
Day:Wednesday April 6
Location:De Anza 1 (Track 1)

Part 2 : Enhanced LC-MS Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Peptides
Richard Gibson, PhD
Thermo Fisher Scientific

Presenter Bio: Richard Gibson is an applications scientist for Thermo Fisher Scientific, based out of San Jose, California. Richard studied mathematics at the University of York and the University of St Andrews before transitioning to biochemistry. He completed his PhD on the biochemical and biophysical characterization of the quartromicin polyketide synthase at the University of Warwick and now works on a range of applications, including peptide quantitation by LC-MS.


Peptide enrichment may facilitate the enhanced LC-MS/MS detection and quantitation of peptides that are signatures of their respective target proteins. Here, an overview of a peptide enrichment technique coupled with bottom-up LC-MS/MS will be discussed and sub/low-femtomole on column absolute quantitation of three peptides from the SARS-CoV-2 nucleocapsid protein will be demonstrated.

For Research Use Only. Not for use in diagnostic procedures.
Thermo Scientific™ Orbitrap™ mass spectrometers are intended for General Laboratory Use Only, and not for Diagnostic or Clinical Use.