= Emerging. More than 5 years before clinical availability. (0.00%)
= Expected to be clinically available in 1 to 4 years. (0.00%)
= Clinically available now. (100.00%)
Percent of confirmed presenters indicating Clinical Use Status: 100.00%



MSACL 2019 US: Conference Program

Palm Springs, California ‚ÄĘ March 31 - April 4, 2019

With Thanks to Our Conference Sponsors:
Shimadzu Thermo
Indigo SCIEX Agilent PerkinElmer
UTAK
And Special Thanks to Our Travel Grant Sponsors:
Brian Kelly
Danyel Tacker
Amadeo Pesce

Sunday

800
1800
Badge Pickup
@ RegDesk @ Ballroom Foyer
1130
1330

Pre-con Workshop(s)

No workshops currently booked for this time period.

1400
1800

Short Course

COURSE START
Clinical MS 301
A Comprehensive Review of Clinical Mass Spectrometry Technology & Techniques, including Miniaturization
Jack Henion, PhD
Level: Intermediate - Advanced
@ TBD
COURSE START
Data Science 101
Breaking up with Excel: An Introduction to the R Statistical Programming Language
Daniel Holmes, MD, Shannon Haymond, PhD & Stephen Master, MD, PhD
Level: Beginner - Intermediate
@ TBD
COURSE START
Data Science 201
Going Further With R: Tackling Clinical Laboratory Data Manipulation and Modeling
Patrick Mathias, MD, PhD & Randall Julian, PhD
Level: Intermediate
@ TBD
COURSE START
Data Science 202
Skyline: A Vendor Neutral Tool for Quantitative Mass Spectrometry
Michael MacCoss, PhD & Brendan MacLean
Level: Beginner - Advanced
@ TBD
COURSE START
Forensic Toxicology 101
Basic Forensic Toxicology
Jarrad Wagner, Ph.D., F-ABFT, Allison Veitenheimer, Ph.D., Russell Lewis, Ph.D., F-ABFT & Robert Johnson, PhD, F-ABFT
Level: Beginner
@ TBD
COURSE START
LC-MSMS 101
Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory
Lorin Bachmann, PhD & Grace van der Gugten
Level: Beginner - Intermediate
@ TBD
COURSE START
LC-MSMS 201
Understanding and Optimization of LC-MS/MS to Develop Successful Methods for Identification and Quantitation in Complex Matrices
Robert D. Voyksner, PhD
Level: Intermediate
@ TBD
COURSE START
LC-MSMS 202
Practical LC-MS Maintenance and Troubleshooting
J. Will Thompson, PhD, Erik J. Soderblom, PhD
Level: Intermediate
@ TBD
COURSE START
LC-MSMS 301
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Brian Rappold, Matthew Crawford and Chris Shuford
Level: Advanced
@ TBD
COURSE START
Metabolomics 201
Application of High Resolution Mass Spectrometry and Metabolomics in Clinical Analysis
Timothy Garrett, PhD & Erin Baker, PhD
Level: Intermediate
@ TBD
COURSE START
Proteomics 201
Clinical Proteomics
Andy Hoofnagle, MD, PhD, Cory Bystrom, PhD & Chris Shuford, PhD
Level: Intermediate - Advanced
@ TBD
1800
2000
Poolside Dinner
@ Poolside
2000
2200
Hospitality Lounge
@ Rocks Patio

Monday

600
900
Breakfast
@ Date
700
1800
Badge Pickup
@ RegDesk @ Ballroom Foyer
730
1130

Short Course

Continued from Sunday
Clinical MS 301
A Comprehensive Review of Clinical Mass Spectrometry Technology & Techniques, including Miniaturization
Jack Henion, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Sunday
Data Science 101
Breaking up with Excel: An Introduction to the R Statistical Programming Language
Daniel Holmes, MD, Shannon Haymond, PhD & Stephen Master, MD, PhD
Level: Beginner - Intermediate
@ TBD
Continued from Sunday
Data Science 201
Going Further With R: Tackling Clinical Laboratory Data Manipulation and Modeling
Patrick Mathias, MD, PhD & Randall Julian, PhD
Level: Intermediate
@ TBD
Continued from Sunday
Data Science 202
Skyline: A Vendor Neutral Tool for Quantitative Mass Spectrometry
Michael MacCoss, PhD & Brendan MacLean
Level: Beginner - Advanced
@ TBD
Continued from Sunday
Forensic Toxicology 101
Basic Forensic Toxicology
Jarrad Wagner, Ph.D., F-ABFT, Allison Veitenheimer, Ph.D., Russell Lewis, Ph.D., F-ABFT & Robert Johnson, PhD, F-ABFT
Level: Beginner
@ TBD
Continued from Sunday
LC-MSMS 101
Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory
Lorin Bachmann, PhD & Grace van der Gugten
Level: Beginner - Intermediate
@ TBD
Continued from Sunday
LC-MSMS 201
Understanding and Optimization of LC-MS/MS to Develop Successful Methods for Identification and Quantitation in Complex Matrices
Robert D. Voyksner, PhD
Level: Intermediate
@ TBD
Continued from Sunday
LC-MSMS 202
Practical LC-MS Maintenance and Troubleshooting
J. Will Thompson, PhD, Erik J. Soderblom, PhD
Level: Intermediate
@ TBD
Continued from Sunday
LC-MSMS 301
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Brian Rappold, Matthew Crawford and Chris Shuford
Level: Advanced
@ TBD
COURSE START
Lipidomics 101
Mass Spectrometry-based Lipidomics and Clinical Applications
Anne K Bendt, PhD, Amaury Cazenave-Gassiot, PhD, Prof Markus R Wenk, Xianlin Han, PhD & Michael Chen, MD MSc
Level: Beginner - Intermediate
@ TBD
COURSE START
MALDI 103
MALDI-MS Fundamentals and its Emerging Role in Pathology and Laboratory Medicine
Mark W. Duncan, PhD & Mari L. DeMarco, PhD DABCC FACB FCACB
Level: Beginner - Intermediate
@ TBD
Continued from Sunday
Metabolomics 201
Application of High Resolution Mass Spectrometry and Metabolomics in Clinical Analysis
Timothy Garrett, PhD & Erin Baker, PhD
Level: Intermediate
@ TBD
Continued from Sunday
Proteomics 201
Clinical Proteomics
Andy Hoofnagle, MD, PhD, Cory Bystrom, PhD & Chris Shuford, PhD
Level: Intermediate - Advanced
@ TBD
COURSE START
Sample Prep 201
Sample Preparation and Alternative Matrices for LC-MS Assays
William Clarke, PhD & Mark Marzinke, PhD
Level: Beginner - Intermediate
@ TBD
1130
1330
Short Course Lunch
@ Date
1230
1630

Short Course

COURSE START
Forensic Toxicology 201
Advanced Forensic Toxicology
Jarrad Wagner, Ph.D., F-ABFT, Allison Veitenheimer, Ph.D., Russell Lewis, Ph.D., F-ABFT & Robert Johnson, PhD, F-ABFT
Level: Intermediate - Advanced
@ TBD
COURSE START
Microbiology 201
Applications of Mass Spectrometry in Clinical Microbiology
Chris Cox, PhD, Kirk Jensen, PhD, Clifton Fagerquist, PhD, Rebecca Harris, MD
Level: Beginner - Intermediate
@ TBD
Continued from Monday AM
Clinical MS 301
A Comprehensive Review of Clinical Mass Spectrometry Technology & Techniques, including Miniaturization
Jack Henion, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday AM
Data Science 101
Breaking up with Excel: An Introduction to the R Statistical Programming Language
Daniel Holmes, MD, Shannon Haymond, PhD & Stephen Master, MD, PhD
Level: Beginner - Intermediate
@ TBD
Continued from Monday AM
Data Science 201
Going Further With R: Tackling Clinical Laboratory Data Manipulation and Modeling
Patrick Mathias, MD, PhD & Randall Julian, PhD
Level: Intermediate
@ TBD
Continued from Monday AM
Data Science 202
Skyline: A Vendor Neutral Tool for Quantitative Mass Spectrometry
Michael MacCoss, PhD & Brendan MacLean
Level: Beginner - Advanced
@ TBD
Continued from Monday AM
LC-MSMS 101
Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory
Lorin Bachmann, PhD & Grace van der Gugten
Level: Beginner - Intermediate
@ TBD
Continued from Monday AM
LC-MSMS 201
Understanding and Optimization of LC-MS/MS to Develop Successful Methods for Identification and Quantitation in Complex Matrices
Robert D. Voyksner, PhD
Level: Intermediate
@ TBD
Continued from Monday AM
LC-MSMS 202
Practical LC-MS Maintenance and Troubleshooting
J. Will Thompson, PhD, Erik J. Soderblom, PhD
Level: Intermediate
@ TBD
Continued from Monday AM
LC-MSMS 301
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Brian Rappold, Matthew Crawford and Chris Shuford
Level: Advanced
@ TBD
Continued from Monday AM
Lipidomics 101
Mass Spectrometry-based Lipidomics and Clinical Applications
Anne K Bendt, PhD, Amaury Cazenave-Gassiot, PhD, Prof Markus R Wenk, Xianlin Han, PhD & Michael Chen, MD MSc
Level: Beginner - Intermediate
@ TBD
Continued from Monday AM
MALDI 103
MALDI-MS Fundamentals and its Emerging Role in Pathology and Laboratory Medicine
Mark W. Duncan, PhD & Mari L. DeMarco, PhD DABCC FACB FCACB
Level: Beginner - Intermediate
@ TBD
Continued from Monday AM
Metabolomics 201
Application of High Resolution Mass Spectrometry and Metabolomics in Clinical Analysis
Timothy Garrett, PhD & Erin Baker, PhD
Level: Intermediate
@ TBD
Continued from Monday AM
Proteomics 201
Clinical Proteomics
Andy Hoofnagle, MD, PhD, Cory Bystrom, PhD & Chris Shuford, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday AM
Sample Prep 201
Sample Preparation and Alternative Matrices for LC-MS Assays
William Clarke, PhD & Mark Marzinke, PhD
Level: Beginner - Intermediate
@ TBD
1730
1930
Dinner on Own
@ YourChoice
1800
2000
Hospitality Lounge
@ Rocks Patio
1830
2030
Faculty Dinner
@ Pueblo

invite only for SciCom, Short Course instructors and CMS journal editors.

Tuesday

600
900
Breakfast
@ Date
700
2000
Badge Pickup
@ RegDesk @ Ballroom Foyer
730
1130

Short Course

Continued from Monday PM
Forensic Toxicology 201
Advanced Forensic Toxicology
Jarrad Wagner, Ph.D., F-ABFT, Allison Veitenheimer, Ph.D., Russell Lewis, Ph.D., F-ABFT & Robert Johnson, PhD, F-ABFT
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Microbiology 201
Applications of Mass Spectrometry in Clinical Microbiology
Chris Cox, PhD, Kirk Jensen, PhD, Clifton Fagerquist, PhD, Rebecca Harris, MD
Level: Beginner - Intermediate
@ TBD
COURSE START
Presentation 101
How to Maximize Your Influence Through Creating Compelling Presentations
Karen Mahooti
Level: Beginner
@ TBD
Continued from Monday PM
Clinical MS 301
A Comprehensive Review of Clinical Mass Spectrometry Technology & Techniques, including Miniaturization
Jack Henion, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Data Science 101
Breaking up with Excel: An Introduction to the R Statistical Programming Language
Daniel Holmes, MD, Shannon Haymond, PhD & Stephen Master, MD, PhD
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
Data Science 201
Going Further With R: Tackling Clinical Laboratory Data Manipulation and Modeling
Patrick Mathias, MD, PhD & Randall Julian, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
Data Science 202
Skyline: A Vendor Neutral Tool for Quantitative Mass Spectrometry
Michael MacCoss, PhD & Brendan MacLean
Level: Beginner - Advanced
@ TBD
Continued from Monday PM
LC-MSMS 101
Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory
Lorin Bachmann, PhD & Grace van der Gugten
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 201
Understanding and Optimization of LC-MS/MS to Develop Successful Methods for Identification and Quantitation in Complex Matrices
Robert D. Voyksner, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 202
Practical LC-MS Maintenance and Troubleshooting
J. Will Thompson, PhD, Erik J. Soderblom, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 301
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Brian Rappold, Matthew Crawford and Chris Shuford
Level: Advanced
@ TBD
Continued from Monday PM
MALDI 103
MALDI-MS Fundamentals and its Emerging Role in Pathology and Laboratory Medicine
Mark W. Duncan, PhD & Mari L. DeMarco, PhD DABCC FACB FCACB
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
Metabolomics 201
Application of High Resolution Mass Spectrometry and Metabolomics in Clinical Analysis
Timothy Garrett, PhD & Erin Baker, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
Proteomics 201
Clinical Proteomics
Andy Hoofnagle, MD, PhD, Cory Bystrom, PhD & Chris Shuford, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Sample Prep 201
Sample Preparation and Alternative Matrices for LC-MS Assays
William Clarke, PhD & Mark Marzinke, PhD
Level: Beginner - Intermediate
@ TBD
800
845

Get the Basics : Lipidomics
An overview of the fundamentals that are driving research and development.

800
1200

Short Course

Continued from Monday PM
Forensic Toxicology 201
Advanced Forensic Toxicology
Jarrad Wagner, Ph.D., F-ABFT, Allison Veitenheimer, Ph.D., Russell Lewis, Ph.D., F-ABFT & Robert Johnson, PhD, F-ABFT
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Microbiology 201
Applications of Mass Spectrometry in Clinical Microbiology
Chris Cox, PhD, Kirk Jensen, PhD, Clifton Fagerquist, PhD, Rebecca Harris, MD
Level: Beginner - Intermediate
@ TBD
COURSE START
Presentation 101
How to Maximize Your Influence Through Creating Compelling Presentations
Karen Mahooti
Level: Beginner
@ TBD
Continued from Monday PM
Clinical MS 301
A Comprehensive Review of Clinical Mass Spectrometry Technology & Techniques, including Miniaturization
Jack Henion, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Data Science 101
Breaking up with Excel: An Introduction to the R Statistical Programming Language
Daniel Holmes, MD, Shannon Haymond, PhD & Stephen Master, MD, PhD
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
Data Science 201
Going Further With R: Tackling Clinical Laboratory Data Manipulation and Modeling
Patrick Mathias, MD, PhD & Randall Julian, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
Data Science 202
Skyline: A Vendor Neutral Tool for Quantitative Mass Spectrometry
Michael MacCoss, PhD & Brendan MacLean
Level: Beginner - Advanced
@ TBD
Continued from Monday PM
LC-MSMS 101
Getting Started with Quantitative LC-MS/MS in the Diagnostic Laboratory
Lorin Bachmann, PhD & Grace van der Gugten
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 201
Understanding and Optimization of LC-MS/MS to Develop Successful Methods for Identification and Quantitation in Complex Matrices
Robert D. Voyksner, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 202
Practical LC-MS Maintenance and Troubleshooting
J. Will Thompson, PhD, Erik J. Soderblom, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
LC-MSMS 301
Development and Validation of Quantitative LC-MS/MS Assays for Use in Clinical Diagnostics
Brian Rappold, Matthew Crawford and Chris Shuford
Level: Advanced
@ TBD
Continued from Monday PM
MALDI 103
MALDI-MS Fundamentals and its Emerging Role in Pathology and Laboratory Medicine
Mark W. Duncan, PhD & Mari L. DeMarco, PhD DABCC FACB FCACB
Level: Beginner - Intermediate
@ TBD
Continued from Monday PM
Metabolomics 201
Application of High Resolution Mass Spectrometry and Metabolomics in Clinical Analysis
Timothy Garrett, PhD & Erin Baker, PhD
Level: Intermediate
@ TBD
Continued from Monday PM
Proteomics 201
Clinical Proteomics
Andy Hoofnagle, MD, PhD, Cory Bystrom, PhD & Chris Shuford, PhD
Level: Intermediate - Advanced
@ TBD
Continued from Monday PM
Sample Prep 201
Sample Preparation and Alternative Matrices for LC-MS Assays
William Clarke, PhD & Mark Marzinke, PhD
Level: Beginner - Intermediate
@ TBD
900
945

Get the Basics : Glycomics
An overview of the fundamentals that are driving research and development.

1000
1045

Get the Basics : Tissue Imaging
An overview of the fundamentals that are driving research and development.

1100
1145

Get the Basics : Data Science
An overview of the fundamentals that are driving research and development.

1230
1345

Lunch Corporate Workshop(s)

Shimadzu
@ Rm5

Workshop summary coming soon ...

Thermo Scientific
@ Rm6

Workshop summary coming soon ...

1400
1415
Welcome Orientation
@ Rooms 2-4
1415

Opening Plenary Lecture


@ Rooms 2-4

1415
1500
Analysis of Exosomes from Patient Serum Samples : Proteomic, Metabolomic and Lipidomic Analyses
David Lubman
University of Michigan Medical Center

We have isolated exosomes from the serum of ten patients with locally advanced pancreatic cancer at serial time points over a course of therapy. We have explored several different methods to purify exosomes in patient serum where it is essential to remove serum proteins including albumin for proteomics studies. Exosomes were identified by using quantitative mass spectrometry. We compared the exosomal proteome of patients at different time points during treatment to healthy controls and identified 8 proteins that show global treatment-specific changes. More recently we have studied changes in the serum exosome metabolome during therapeutic treatment where specific metabolites and lipids may be markers of treatment. The differential content of exosomes during a course of therapy suggests that exosomes may provide novel insights into the development of treatment resistance and metastasis.

1515
1615

State of the Science Address
@ Rooms 2-4

Presented by MSACL US Scientific Committee Topic Leads, this address will provide an overview of the applications and technologies currently being used in Clinical Labs, and a clear view of the development pipeline. It will highlight applications expected to be available in the near-future, as well as emerging applications, and key contributors. Relevant talks, posters, and people present at the congress will be identified, enabling you to optimize your learning path and more effectively target potential network connections. Whether you are new to Clinical Mass Spectrometry, or a seasoned veteran, the State of the Science address should be on your agenda.
1615
1630
Intermission
@ Ballroom Foyer
1630
1700
Poster Lightning Talks
@ Rooms 2-4

90 seconds, one slide. Up to 15 poster presentations highlighted.
1700
1730
Vendor Lightning Talks
@ Rooms 2-4

90 seconds, one slide. Up to 20 vendors highlighted.
1730
2000
Exhibits Dinner Reception
@ Exhibit Hall in Oasis 3-4
1800
1900
Meet-a-Mentor: Booth Tours
@ Exhibit Hall in Oasis 3-4

Join a mentor as they tour the booths and learn more about technologies available, what mentors are looking for during the exchange, and how they interact with the booth vendors. Increase your network and your knowledge of products and services available.
1900
2000
Troubleshooting Forum: Poster Round
@ Exhibit Hall in Oasis 3-4

Join the troubleshooting poster discussion to learn something new or add your two cents.
No Troubleshooting Posters have yet been booked for this event.

2000
2100

Discussion Group

2000
2200
Hospitality Lounge
@ Rocks Patio
2100
2400
The Speakeasy
@ TBA

Wednesday

630
815
Breakfast
@ Ballroom Foyer

Pre-Workshop Breakfast
700
1800
Badge Pickup
@ RegDesk @ Ballroom Foyer
700
745

Corporate Workshop(s)

Biotage
@ Rm3

Workshop summary coming soon ...

Indigo BioAutomation
@ Rm4

Workshop summary coming soon ...

Thermo Scientific
@ Rm5

Workshop summary coming soon ...

745
800
Intermission
@ Ballroom Foyer
800
845

Corporate Workshop(s)

Restek
@ Rm1

Workshop summary coming soon ...

SCIEX
@ Rm2

Workshop summary coming soon ...

Thomson Instrument Co
@ Rm3

Workshop summary coming soon ...

Agilent Technologies
@ Rm4

Workshop summary coming soon ...

MilliporeSigma
@ Rm5

Workshop summary coming soon ...

845
900
Intermission
@ Ballroom Foyer

Scientific Session 1

Pueblo

MALDI Imaging
Chair: TBA

Room 1

Results of a Survey on Diagnostic Laboratory Metadata QA Practice
Chair: TBA

Room 2

Breath in Breath out: Analysis of non-Invasive Matrices
Chair: TBA

Room 3

New Technologies and Approaches in Metabolomics
Chair: TBA

Room 4

Proteomics: Discovery/Translation
Chair: TBA

Room 5

Wrangling Raw Data
Chair: TBA

900
920
MALDI Imaging MS: Transforming Drug Discovery and Development through Molecular Images of Biological Systems
Steve Castellino
GlaxoSmithKline
A Survey of Mass Spectrometry Quality Assurance Practices in Clinical Laboratories
Joshua Hayden
Norton Healthcare
Cannabinoid Concentrations in Whole Blood, Oral Fluid, and Breath After Recent Use
Jacqueline Hubbard
University of California, San Diego
Sub-Microliter Metabolomics via Inductive Triboelectric Nanogenerator Mass Spectrometry
Yafeng Li
Georgia Institute of Technology
A Proteomic Predictor of Lipoprotein Function and Coronary Artery Disease: From Conception to Launch
Timothy Collier
Quest Diagnostics - Cleveland HeartLab
Impact of Discretized Intensities on Accuracy and Precision of LC-MS/MS Results
Fred Lytle
Indigo BioAutomation, Inc.
920
940
...
Keynote
...
...
Extended Session
...
A Novel Derivatization Method for High-Sensitivity LC-MS/MS Analysis of Aromatic Compounds
Y. Ruben Luo
University of California at San Francisco
Rapid Bile Acid Isomer Separation with Ion Mobility-Mass Spectrometry
Robin Kemperman
University of Florida
Mass Spectrometry-based Quantitative Diagnostic Test of Allograft Kidney using Targeted Proteome Profiling of FFPE Specimens
Kunhong Xiao
University of Pittsburgh
Chemical Fingerprints of Biofluids. Building Tandem Mass Spectral Libraries of Recurrent Spectra
Yamil Simón-Manso
National Institute of Standards and Technology
940
1000
...
Keynote
...
...
Extended Session
...
Monitoring of Acetone and Short Chain Fatty Acids Levels in Mouth and Nose Breath following Fasting and Re-Feeding with Selected Ion Flow Tube Mass Spectrometry
Ilaria Belluomo
Imperial College London
Development of a 18-plex UPLC-MS/MS Assay for Newborn Screening of Lysosomal Storage Disorders and Other Treatable Genetic Diseases
Xinying Hong
University of Washington
Development of a Proteomic Plasma Biomarker Panel for Hypertrophic Cardiomyopathy
Wendy Heywood
University College London
Improving the Sensitivity and Accuracy of Quantitative Protein Biomeasure Mass Spectrometry Through the Use of a SRM Transition Summing Technique
Jay Johnson
Pfizer Worldwide Research and Development
1000
1100
Exhibits & Poster Session
@ Exhibit Hall in Oasis 3-4

Positions A to be attended.

Scientific Session 2

Pueblo

New Developments in MS Imaging Technologies
Chair: TBA

Room 1

Practical Training : Development of a Quantitative Protein Assay
Chair: TBA

Room 2

Vitamins: Analytical gains for clinical pains
Chair: TBA

Room 3

Metabolic profling
Chair: TBA

Room 4

Proteomics: Discovery/Translation II
Chair: TBA

Room 5

Data Science Keynote
Chair: TBA

1100
1120
Practical Method for Molecular Imaging with Single-Cell Resolution and Very High Speed
Marvin Vestal
SimulTOF Systems of Virgin Instruments Corp
Part I: Digest Optimization and Quality Control for Proteomic Assays
Timothy Collier
Quest Diagnostics - Cleveland HeartLab
Association of Free and Total 25 Hydroxy Vitamin D with Biomarkers of Polycystic Ovary Syndrome
Mark Kushnir
ARUP Institute for Clinical & Experimental Patholo
Metabolomic Profiling of a Large Cohort of Glioblastoma Stem Cell Lines Identifies Pathways Associated with Clinical Outcome
Olga Zaslaver
University of Toronto
Clinical Proteomics Enters Clinical Trials: A Generic GCP-compliant Workflow for the Routine Analysis of FFPE Tissue Samples by Quantitative Mass Spectrometry
Axel Ducret
F. Hoffmann-La Roche Ltd
Towards Automated Quality Assessment and Analysis of Targeted Mass Spectrometry Data using Machine Learning
Shadi Eshghi
Genenech
1120
1140
A Combination Analysis of DESI-MSI with Laser Capture Microdissection using Same Tissue Section
Emine Kazanc
Imperial College of London
Developing a Protein LC-MS/MS Assay: A Small Molecule Girl Goes Big! (Or, if I can do it, so can you!)
Grace van der Gugten
St Paul's Hospital
Vexed by Vitamins-Conform, Confirm or Create?
Hemamalini Ketha
Laboratory Corporation of America Holdings
Vascular Biomarkers to Predict Response to Exercise in Alzheimer’s Disease
Danni Li
University of Minnesota
Nanoliter-Scale Oir-Air-Droplet Chip-based Single Cell Proteomics Analysis
Catherine CL Wong
CPMMR, Health Science Center, Peking University
...
Keynote
...
1140
1200
Multimodal Imaging Mass Spectrometry Technologies to Visualize Staphylococcal Molecular Adaptation within the Infectious Microenvironment
William Perry
Vanderbilt University
...
Extended Session
...
Strategies for Developing High-Throughput Mass Spectrometry Analyses of 25-Hydroxyvitamin D
Richard Yost
University of Florida
Nitisinone: Short and Long Term Effects on Tyrosine Metabolites in Alkaptonuria and Unmasking of the Ochronotic Pathway
Anna Milan
Royal Liverpool University Hospital
TBA...
Keynote
...
1200
1300
Lunch
@ Exhibit Hall in Oasis 3-4

Scientific Session 3

Pueblo

Keynote : Glycans in Tissue Imaging
Chair: TBA

Room 1

Practical Training : Resolving Non-Specific Binding in qLC-MSMS
Chair: TBA

Room 2

Current MS advances for pain management: moving beyond the urine drug screen
Chair: TBA

Room 3

Multiomics
Chair: TBA

Room 4

MALDI and Intact Protein Analysis
Chair: TBA

Room 5

Micro I
Chair: TBA

1300
1320
Application of N-Glycan MALDI MS Imaging to Identify Cancer Biomarker Signatures in FFPE Tissues and Biofluids
Richard Drake
Medical University of South Carolina
Non-Specific Binding in LC-MS/MS Bioanalysis: What is it and How to Deal with It?
Jack Henion
Advion, Inc
A High Resolution Mass Spectrometry Method for Detecting a Comprehensive Pain-Management Drug Panel in Oral Fluid
Adina Badea
University of California, San Francisco
A Multi-omic Investigation of Molecular Signatures Indicative of Preeclampsia and Gestational Diabetes
Melanie Odenkirk
North Carolina State University
Diagnosis of Hemoglobinopathy and Beta Thalassemia by 21 Tesla Fourier Transform Ion Cyclotron Resonance MS and Top-Down MS/MS of Hemoglobin from Blood
Lidong He
University of Virginia
Mapping Pathogenesis: A Systems-Level Investigation of GBS Meningitis
Anaamika Campeau
UC San Diego
1320
1340
...
Keynote
...
...
Extended Session
...
MALDI-MS-based Validation of a 110 SNV Pharmacogenomic Panel for Pain Management Providers
Grace Williams
Dartmouth-Hitchcock Medical Center
Investigating the Skin Metabolome using Untargeted Metabolomics and the Initial Development Towards Non-Invasive Drug Monitoring
Alan Jarmusch
University of California, San Diego
Combining MALDI-TOF Serum Profiling and Top-Down Protein Analysis with 21 T FT-ICR Mass Spectrometry for Proteoform Identification
Nathan Kaiser
Biodesix
Rapid Determination of Methicillin-Resistant Staphylococcus Aureus by MALDI-TOF MS and Machine Learning
Taojunfeng Su
Weill Cornell Medicine
1340
1400
...
Keynote
...
...
Extended Session
...
Comparison of a Coated Blade Spray - Mass Spectrometry (CBS-MS) Method vs a Point of Care (POC- CUP) Test for the Drug Screening in Chronic Pain Patients
Shirin Hooshfar
University of California San Francisco
Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines Toward Enhanced Oxidative Phosphorylation
Haiwei Gu
Arizona State University
Utilizing Protein Signatures from Heterogeneous Cell Populations in a Murine Model for Diagnosis of Ovarian Cancer
Melissa Galey
University of Illinois at Chicago
Top-Down Analysis of the B-Subunit of Shiga Toxin from Escherichia coli using MALDI-TOF-TOF Mass Spectrometry: Asparagine and the Aspartic Acid Effect Mechanism
Clifton Fagerquist
Agricultural Research Service, WRRC, USDA
1400
1500
Exhibits & Poster Session
@ Exhibit Hall in Oasis 3-4

Position B to be attended.
1415
1500
Meet-a-Mentor: Poster Tours 1
@ Exhibit Hall in Oasis 3-4

Join a mentor as they tour the posters. Learn more about what mentors are looking for in a poster, and how they engage the presenter.

Scientific Session 4

Pueblo

Environmental Contaminants
Chair: TBA

Room 1

Practical Training : Interpretation of Urine Drug Testing Results for Pain Management
Chair: TBA

Room 2

New Analytical Approaches to Standard Analytes
Chair: TBA

Room 3

New Methods in Metabolomics
Chair: TBA

Room 4

Proteomic Applications to Chronic Kidney Disease
Chair: TBA

Room 5

Keynote: Maximizing the Performance of MALDI-TOF MS-based Microbial Characterization
Chair: TBA

1500
1520
Mass Spectrometry: Applications to the Hospital Blood Bank
Joesph Wiencek
University of Virginia School of Medicine
Interpretation of Urine Drug Testing Results for Pain Management
Alec Saitman
Providence Regional Laboratories
MS & MS: Micro Sampling & Mass Spectrometry
Matthew Crawford
LabCorp
GC-MS Targeted Screening of Different Metabolite Classes for Prostate Cancer and Prostate Hyperplasia Patients and Searching for Potential Biomarkers
Pavel Markin
Sechenov First Moscow State Medical University
Proteomic Genotyping: When Quantitation Doesn’t Matter, But Quality Still Does
Christopher Shuford
Laboratory Corporation of America
Maximizing the Performance of MALDI-TOF MS-based Microbial Characterization: Challenges, Strategies, and Successes Beyond Species-level and Pure Culture Applications
Todd Sandrin
Arizona State University
1520
1540
Analysis of Urinary Biomarkers of Exposure to Volatile Organic Compounds from the Population Assessment of Tobacco and Health (PATH) Study (Wave 1)
Victor De Jesus
Centers for Disease Control and Prevention
...
Extended Session
...
Multi-Point Internal Calibration: IntrinsiX LC-MS/MS Analysis of Methotrexate
Melissa Hoffman
University of California, San Diego
A Novel Approach for the Classification and Detection of Pathological Pain
Meritxell Deulofeu Figueras
University of Girona
Apolipoprotein L1 is Associated with Larger HDL Particles in CKD
Andy Hoofangle
Unversity of Washington
...
Keynote
...
1540
1600
Environmental Antibiotic Exposure in Pregnancy
Zheng Cao
Beijing Obstetrics & Gynecology Hospital
...
Extended Session
...
The Impact of Remote Monitoring in Pediatric Renal Transplant Patients: Multiplexed Quantification of Immunosuppressants and Creatinine by LC-MS/MS
Jane Dickerson
Seattle Children's Hospital
Novel Headspace Sorptive Extraction on Urinary Volatile Organic Compounds for Oesophago-Gastric Cancer Detection
Qing Wen
Imperial College London
Development of a Parallel Reaction Monitoring Workflow for Biomarker Verification in Chronic Kidney Disease
Angela Mc Ardle
Cedars Sinai Medical Center
...
Keynote
...
1600
1730
Exhibits & Appetizers
@ Exhibit Hall in Oasis 3-4
1615
1700
Meet-a-Mentor: Office Hours 1
@ Exhibit Hall in Oasis 3-4

Have a question from the congress that you have been itching to ask? Or a problem from work that you want to get feedback on? Or feedback on the congress? Sign up at the registration desk for 15-min blocks to share time and ideas with a mentor in a relaxed setting.
1615
1715
Troubleshooting Forum: Poster Rounds
@ Exhibit Hall in Oasis 3-4

Join the troubleshooting poster discussion to learn something new or add your two cents.
No Troubleshooting Posters have yet been booked for this event.

1715
1730
Plenary Reception
@ Ballroom Foyer
1730

Distinguished Contribution Award Plenary Lecture


@ Rooms 2-4
Chair: Distinguished Contribution Award Committee

1730
1830

On the Award

Immunotherapy of Cancer and the Role of Mass Spectrometry; An Overview and New Results
Donald Hunt
University of Virginia

This lecture will describe how the immune system works to keep us free of cancer most of the time and how cancer cells can eventually learn to escape the immune system. Also described will be a number of scientific breakthroughs that have occurred in the last 6 years that clearly suggest that the immune system can be re-educated and upregulated to cure even late stage cancer. Science magazine labeled cancer immunotherapy as the breakthrough event of the year in 2013 and tremendous progress has been made since then. James Allison won the 2015 Lasker Award and shared the 2018 Nobel Prize in Medicine with Tasuku Honjo for their work to reactivate the immune system to fight cancer. This lecture will try capture some this excitement and also pinpoint some of the contributions that the Hunt group has made to the field over the past 25 yrs.

1830
2200
FREE EVENING / OFF-SITE MEETINGS / DINNER ON OWN
@ YourChoice

Haven't decided on a dinner location yet? Head to the Hospitality Lounge at Rocks Patio to meet up with old friends or make new ones over drinks and light appetizers before heading to dinner in Palm Springs.
1830
2200
Hospitality Lounge
@ Rocks Patio
2100
2400
The Speakeasy
@ TBA

Thursday

730
815
Breakfast
@ Ballroom Foyer

Pre-Workshop Breakfast
800
845

Corporate Workshop(s)

Waters
@ Rm1

Workshop summary coming soon ...

Ceres Nanosciences
@ Rm2

Workshop summary coming soon ...

PerkinElmer
@ Rm3

Workshop summary coming soon ...

MSACL
@ Rm4

The Status of Clinical Mass Spectrometry in China
Chaired by David Herold

1. Chengbin Wang - Chairman of Chinese Society of Laboratory
Medicine, Chairman Chinese Association for Mass Spectrometry in the
Clinical Lab.

2. Development of Clinical MS in the University Setting
Wei Guo (Fudan University)

3. Zhouyang Kang (Dian Labs Hangzhou)

4. Keqi (Jacky) Tang (Ningbo University)

Thermo Scientific
@ Rm5

Workshop summary coming soon ...

845
900
Intermission
@ Ballroom Foyer
900
1000
Exhibitor Feedback Meeting
@ Mesquite H

Scientific Session 5

Pueblo

MS Imaging in Clinical Applications
Chair: TBA

Room 1

Practical Training : How Programming Will Save You Time
Chair: TBA

Room 2

Small Molecule Hot Topics: It's Not Monkey Business
Chair: TBA

Room 3

Lipidomics in Disease Diagnostics
Chair: TBA

Room 4

TBA
Chair: TBA

Room 5

Micro II
Chair: TBA

900
920
Desorption Electrospray Ionization Mass Spectrometry as a Tool for Diagnosis of Thyroid Nodules from Fine Needle Aspiration Biopsies
Rachel DeHoog
University of Texas at Austin
Making a Case for Why Programming Will Save You Time
Shannon Ellis
University of California San Diego
Development of an LC-MS/MS Method for Assessment of Mutant Isocitrate Dehydrogenase (mIDH) Cancer Biomarkers in Acute Myeloid Leukemia
Jeffrey Whitman
University of California, San Francisco
Investigating Smooth Muscle Foam Cells in Atherosclerosis ‚Äď Applications of Tandem Mass Spectrometry
Joshua Dubland
University of British Columbia
TBA Metabolomics of Oxalobacter Formigenes to Characterize Intestinal Oxalate Secretion
Casey Chamberlain
University of Florida
920
940
Intraoperative-MS-based Biopsy Analysis Platform for Glioma Diagnosis, Extent of Tumor Cell Infiltration Estimation, and IDH Subtyping
Clint Alfaro
Purdue University
...
Extended Session
...
Mass Spectrometry and Mass-Overdose in New Haven, Connecticut
Dustin Bunch
Yale-New Haven Hospital
Sterol Profile Analysis for Cholesterol Biosynthesis Disorders by Label-Free LC-MS/MS
Matthew Nichols
Post- Doctoral Fellow
TBA Analytical Strategies to Study the Interaction Between Microbiota and Drug Metabolism using Targeted and Untargeted LC-MS-based Metabolomics
Marine Letertre
Imperial College London
940
1000
Rapid Evaporative Ionization Mass Spectrometry Explores Tumor Necrosis and Tissue Autolysis
Pierre-Maxence Vaysse
Maastricht University
...
Extended Session
...
Analysis of Steroid Hormones in Serum and Follicular Fluid of Female Rhesus Macaques with Chronic Combined Hyperandrogenemia and/or Western-Style Diet
David Erikson
Oregon National Primate Research Center
Lipidomic Profiling of Extracellular Vesicles Released by Breast Cancer Cells and their Potential as Body-Fluid Based Biomarkers for Breast Cancer Detection
Erika Dorado
Imperial College London
TBA Developing Laser Assisted Rapid Evaporative Ionization Mass Spectrometry (LA-REIMS) as an Automated High-Throughput Platform for Clinical Microbiology
Simon Cameron
Imperial College London
1000
1100
Exhibits & Poster Session
@ Exhibit Hall in Oasis 3-4

Positions C to be attended.
1015
1100
Meet-a-Mentor: Poster Tours 2
@ Exhibit Hall in Oasis 3-4

Join a mentor as they tour the finalist in the student poster competition.

Scientific Session 6

Pueblo

MS Imaging to Investigate Disease Behavior
Chair: TBA

Room 1

Practical Training : Everything You Wanted to Know About Internal Standards But Were Too Afraid to Ask
Chair: TBA

Room 2

Natural Products
Chair: TBA

Room 3

Keynote: Translation of Lipidomic Technologies Towards Quantification of Blood Lipids
Chair: TBA

Room 4

New Proteomic Assays
Chair: TBA

Room 5

Machine Learning
Chair: TBA

1100
1120
Spatial Metabolomics Identifies a Glomerular Sphingomyelin as a Potential Therapeutic Target for the Treatment of Diabetic Kidney Disease
Guanshi Zhang
UT Health San Antonio
Everything You Wanted to Know about Internal Standards But Were Too Afraid to Ask
Russ Grant
Labcorp
View Slides (PDF)

Clinical Evaluation of Interaction of Phytoestrogenic Botanical Dietary Supplements with Drug Metabolism in Women
Luying Chen
Linus Pauling Institute, Oregon State University
Translation of Lipidomic Technologies Towards Quantification of Blood Lipids
Markus Wenk
National University of Singapore
Development of a Fit-For-Purpose LC-MRM-MS Assay to Measure Prion Protein in Cerebrospinal Fluid
Eric Kuhn
Broad Institute
Automating HPLC Peak Detection using Convolutional Neural Networks
Matthew Boutell
Rose-Hulman Institute of Technology
1120
1140
Predicting an Early Response of Tissue to Pharmacological Treatment Prior to Changes in Histology
Katy Margulis
Stanford University
...
Extended Session
...
Hormone Modulations of 4-Hydroxyestradiol, 5a-Androstane-3a,17β-diol, and Glucocorticoids in Urine of Menopausal Women Taking a Hop Botanical Dietary Supplement
Alan Wong
Linus Pauling Institute, Oregon State University
...
Keynote
...
A LC-MS/MS Method using Antibody Free Sample Preparation for Multiplexed Targeted Quantitative Intact Protein Biomarkers of Diabetes from Human Serum
Jesse Seegmiller
University of Minnesota
High-Throughput Metabolomics Combined with Artificial Intelligence for Prognostic and Diagnostic Assessments
Jacques Corbeil
Laval University
1140
1200
Imaging Mass Spectrometry Reveals Crosstalk Between the Fallopian Tube and the Ovary that Drives Primary Metastasis of Ovarian Cancer
Laura Sanchez
University of Illinois at Chicago
...
Extended Session
...
Cannabinoidomics ‚Äď An Analytical Tool to Understand the Effect of Medical Cannabis Treatment
Paula Berman
Technion - Israel Institute of Technology
...
Keynote
...
Early Prediction of Cardiac Events via Remote Monitoring Coupled with an Apolipoprotein Targeted MRM Panel
Kelly Mouapi
Cedar-Sinai Medical Center
TBA
1200
1300
Lunch
@ Exhibit Hall in Oasis 3-4

Scientific Session 7

Pueblo

TBA
Chair: TBA

Room 1

Practical Training : TDM with LC-MSMS
Chair: TBA

Room 2

Drug Analysis: Monitoring Efficacy and Detecting Exposure
Chair: TBA

Room 3

Metabolomics & Imaging
Chair: TBA

Room 4

Neuroproteomics
Chair: TBA

Room 5

Applied Informatics
Chair: TBA

1300
1320
TBA Potential to Improve Patient Care: Therapeutic Drug Monitoring (TDM) using LC-MS/MS
Paul Jannetto
Mayo Clinic
Tape Stripping and High Performance LC-MS/MS Measuring Chlorhexidine Gluconate on Skin
Xueheng Zhao
Cincinnati Children's Hospital Medical Center
Assessing the Effect of Nitisinone Induced Hypertyrosinaemia on Monoamine Neurotransmitters in a Murine Model of Alkaptonuria using Mass Spectrometry Imaging
Andrew Davison
University of Liverpool
A Comprehensive Map and Functional Annotation of the Normal Human Cerebrospinal Fluid Proteome
Yajie Wang
Dept of Clinical Laboratory, Beijing Ditan Hosp
No Typing Allowed: Reflections and Advice One Year After Automating All Mass Spectrometry Result Entry at a Regional Clinical Reference Laboratory
Benjamin Beppler
TriCore Reference Laboratories
1320
1340
TBA...
Extended Session
...
Quantification of Superwarfarin Rodenticides in Plasma using High-Performance LC-MS/MS
Daniel Nosal
Oregon State University - Linus Pauling Institute
Ambient Ionization Mass Spectrometry Imaging for Prognostic Metabolic Signatures in Clear Cell Renal Carcinoma (ccRCC)
Vijaya Lakshmi Kanchustambham
Stanford University
Screening for Alzheimer’s Disease: Summary and Future Directions of an Amyloid-Beta Blood Test
Melissa Budelier
Washington University in St Louis
Clinical Mass Spectrometry Workflow Improvements by Transitioning from Manual to Auto-Data Review
Alec Saitman
Providence Health and Services
1340
1400
TBA...
Extended Session
...
Concordance of Paired Maternal and Newborn Urine Drug Screens using Low Cutoffs for Positivity
Stephen Roper
Washington University School of Medicine
Spatially Resolved Analysis of Thermally Injured Skin using Desorption Electrospray Ionisation Mass Spectrometry Imaging
Josh Cuddihy
Imperial College London, UK
TDP-43 Enrichment using a High Affinity RNA Aptamer
Taylor Pobran
University of British Columbia
Monitoring Clinical Mass Spectrometry System Performance
Shannon Haymond
Northwestern University
1400
1530
Exhibits & Poster Session
@ Exhibit Hall in Oasis 3-4

Positions D to be attended.
1430
1530
Meet-a-Mentor: Office Hours 2
@ Exhibit Hall in Oasis 3-4

Have a question from the congress that you have been itching to ask? Or a problem from work that you want to get feedback on? Or feedback on the congress? Sign up at the registration desk for 15-min blocks to share time and ideas with a mentor in a relaxed setting.
1515
1530
Remove Posters
@ Exhibit Hall in Oasis 3-4

You can store your poster between Smoketree F and Rm6 until 20:00.
1515
1630
Plenary Reception
@ Ballroom Foyer
1530
Exhibits Closed
@ Exhibit Hall in Oasis 3-4
1530

Plenary Lecture


@ Rooms 3-4

1530
1615
Tools and Infrastructure to Enable Crowdsourcing the Molecular Analysis of Microbiome as Applied to Precision Care
Pieter Dorrestein
University of California, San Diego

The general community is encouraged to visit the same primary care physician. This is because they ‚Äúknow‚ÄĚ their patients. This means that when the physician observes changes or upon request of the patient, a physician may request additional tests to be performed such as measuring small molecules. Cholesterol, lipids, thyroid hormones, and serotonin levels are representative examples. If these molecules are out of the norm, or dramatically change from previously measured levels, an intervention may be prescribed. In recent years OMICS technologies, including informatic capabilities, have advanced significantly and has led to the increasing recognition that a person is a walking ecosystem not only comprised of human cells but also bacteria, fungi and other eukaryotes and phages, collectively called the microbiome. In addition that when the microbiome defines the health and disease status of the host as well as how a patient responds to interventions such as medications. Monitoring the changes due to the microbiome is difficult but, in principle, if we can perform untargeted OMICS analysis of patient samples, it can be expected that such monitoring can be used by physicians to understand their patients. This presentation describes how research grade untargeted mass spectrometry and microbiome sequencing based OMICS technologies can be used to understand the disease and the effect of treatments. This is achieved through building crowd sourced community knowledge capture, analysis, and data visualization infrastructures and apply them via close interactions with physicians. The ability as will be highlighted in this presentation via providing large scale data analysis and visualization capabilities at clinical relevant time scales represents the tip of the iceberg of what future technologies may bring. We will showcase these capabilities through highlighting the early versions of these capabilities that has processed 100,000s of samples. Examples will be shown associated with inflammatory diseases, liver disease, metabolism, cardiac disease, infectious disease, sleep deprivation, malnutrition but also several single patient case studies, including a single patient phage therapy treatment.

1615
1630
Intermission
@ Ballroom Foyer
1630
1800
FDA Viewpoint
@ Rooms 3-4

FDA Overview of the Process for Clearance and Approval of Mass Spectrometry-based In vitro Diagnostic Devices with Doug Jeffery, Majda Haznadar & Yvonne Shea
1800
1815
Poster Awards
@ Rooms 3-4

Join us in congratulating the winners of the poster contest.
1815
1830
Final Remarks
@ Rooms 3-4

The Scientific Committee Chair and Vice Chair wrap up the week and share information about upcoming Conferences.
1830
2000
Closing Dinner
@ Ballroom Foyer

A final seated meal and opportunity to relax into the evening. After your meal, you may choose to wander downtown to explore Village Fest - http://villagefest.org/.
1930
2200
Hospitality Lounge
@ Rocks Patio
2200
Conference Closed
@ Ballroom Foyer

Friday

830
1000
SciCom Meeting
@ TBA

A private gathering for SciCom members to reflect on the week and brainstorm ideas for the coming conference. Brunch. 1. Establish topics of particular interest to highlight in 2020, allowing SciCom members ample time to solicit and formulate programming. 2. Of particular interest is science that appeals to multiple topic areas, and can encourage communication between disciplines. 3. Begin thinking about nominations for 2020 Keynotes/Plenaries. Conduct a brief post-con evaluation of what worked/what can be improved. 4. Confirm 2020 Committee members.