Technology & Data Science for Enhanced Patient Care

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EUROPE 2015

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Presented at 2015_EU

Why High-resolution-MS Is Becoming the New Gold Standard MS Analyzer in Clinical Labs
Bertrand Rochat
CHUV - qMSF

As we see more and more demonstrations of the capability of high-resolution (HR)-MS instruments to perform sensitive and reliable quantification of a large variety of analytes in HR-full scan mode, we can consider that HRMS is the new gold standard MS analyzer for LCMS analyses (quantitative and qualitative). Examples showing the versatility and the performances of HRMS in HR-full scan will be presented: 1) routine quantification of drugs and endogenous metabolites in plasma extracts, 2) Qual/Quan analysis in a study of the fate of tamoxifen drug in humans and 3) targeted and untargeted metabolomics.

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