Overcoming the challenges of implementing high value tests in the clinical lab

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Educational Grants supported in part by:
& Brian Kelly

Agenda (Preliminary) - View Program

Wednesday, April 6

Time

Sessions

Registration Desk Opens

Location: De Anza Foyer

Round Table Interest Groups

Location: De Anza Foyer

(1) On Being a Reviewer
with Tim Garrett

(2) Follow on discussion about convincing admin that they need to buy a mass spectrometer
with Joshua Hayden

(3) Shortcomings / Limitations of Antinuclear Antibodies (ANA) : Stark Disparities - Multiplex Vs. Immunofluorescence Assay
with Mahesheema Ali

(4) Tissue Imaging
with Michael Angelo, Laura Sanchez, David Herold

Glycoproteins as Biomarkers for Cancers

Location: De Anza

Carlito Lebrilla, PhD

UC Davis

The path from fundamental discoveries with MS to translation and commercialization.

How Can Proteomics Fulfill the Unmet Needs of Effective Drug Treatment Stratification for Patients with Ovarian Cancer?

Location: De Anza

Stefani Thomas, PhD, DABCC, NRCC

University of Minnesota

The mutational status of a solid tumor can predict the therapeutic efficacy of a specific drug in a molecularly defined subset of patients. Targeted therapies are available to treat advanced (stage II – IV) ovarian cancer with mutations in BRCA1/2 genes. Unfortunately, there is considerable inter-patient heterogeneity in BRCA1/2–based determinations of drug treatment sensitivity. Determining the proteome-level mechanisms of drug treatment sensitivity could enhance our ability to select the ovarian cancer patient populations that would benefit the most from these targeted therapies, consequently improving survival and overall treatment response. Our laboratory is applying mass spectrometry-based proteomics to identify protein signatures of drug treatment sensitivity and subsequent patient stratification for treatment. This presentation will provide an overview of the experimental models and analytical approaches that we are utilizing toward a long-term goal of identifying prognostic protein biomarkers of drug treatment sensitivity in patients with high-grade serous ovarian cancer.

Coffee Break

Location: Exhibit Hall - Serra

N-linked Glycans in Human Disease: From New Tools to Translational and Preclinical Studies

Location: De Anza

Peggi Angel, PhD

MUSC Proteomics Center

N-glycosylation plays a significant role in immune cell recruitment, influences disease progression and outcome and response to therapy. Here, we discuss simplified workflows capable of reporting N-glycan expression patterns in tissues, cells and biofluids. We present translational and pre-clinical work investigating glycosylation patterns in cardiovascular disease, cancer risk and cancer. A long-term goal is to leverage glycosylation patterns to non-invasively monitor disease status and therapeutic efficacy.

Panel Discussion

Location: De Anza

Poster Session

Location: Exhibit Hall - Serra

Industry Workshop : Thermo Fisher Scientific

Location: De Anza 1

Industry Workshop : Thermo Fisher Scientific

Location: De Anza 2

Industry Workshop : Agilent Technologies

Location: De Anza 3

Poster Session

Location: Exhibit Hall - Serra

Scientific Session 1
Endogenous Small Molecules

Location: De Anza 1

Scientific Session 1
Glycomics and Proteomics of SARS-CoV2 Immunology

Location: De Anza 2

Scientific Session 1
Taking it to the Top: Reference Methods and Materials

Location: De Anza 3

Scientific Session 1

Location: Bonsai

Coffee Break

Location: Exhibit Hall - Serra

Scientific Session 2
Rapid Detection and Quantitation via Ambient Ionization

Location: De Anza 1

Scientific Session 2
Tissue imaging - Dynamics and Mapping

Location: De Anza 2

Scientific Session 2
Starting Right - The Life of a Sample from Tube to Bench

Location: De Anza 3

Scientific Session 2

Location: Bonsai

Coffee Break

Location: Exhibit Hall - Serra

Scientific Session 3
Steroids - Methods and Matricies

Location: De Anza 1

Scientific Session 3
Proteomics - New Methods and Continuous Improvement

Location: De Anza 2

Scientific Session 3
Data - Integrating, Mapping and Reporting

Location: De Anza 3

Scientific Session 3

Location: Bonsai

Happy Hour in the Exhibit Hall

Location: Exhibit Hall - Serra

Troubleshooting Posters

Location: Exhibit Hall - Serra

Dinner on Own

Location: Off-site

Check out one of the many restaurants on Alvarado Street.

Hospitality Reception

Location: Jacks

Inside of Jacks Club Room (Portola Hotel)

Meet up with friends for light drinks on your way out to dinner at one of the many restaurants on Alvarado Street.

FeMS Networking Event - Separate Registration Required

Location: Ferrantes

Visit Reg Desk to inquire if interested in participating.