Lipid Imaging for Cancer Diagnosis by Ambient Ionization Mass Spectrometry
Livia S. Eberlin
The University of Texas at Austin
There is a clinical need for new technologies that would enable rapid disease diagnosis based on diagnostic molecular signatures. Ambient ionization mass spectrometry has revolutionized the means by which molecular information can be obtained from tissue samples in real time and with minimal sample pretreatment. The latest developments in ambient ionization techniques applied to clinical research suggest that ambient ionization mass spectrometry will soon become a routine medical tool for tissue diagnosis. This talk will cover the main developments in ambient ionization techniques applied to lipid imaging and tissue analysis, with focus on the use of desorption electrospray ionization mass spectrometry for cancer diagnosis. Recent approaches to incorporate this technology for routine, clinical use in the treatment and management of cancer patients will be discussed.
Presented at MSACL 2016 US