Accelerating the Implementation of Mass Spectrometry in the Clinical Lab

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EUROPE 2018

Help Us Reach Our Educational Support Goal of $40,000
Educational Travel Grants supported in part by:

Meet-the-Experts

MSACL strives to offer a congress experience that values training and mentorship (see travel grants, short courses and Practical Training tracks), and provides avenues by which early-career attendees can gain experience presenting (see Poster Lightning Talks, the Poster Contest, Podium opportunities).

The Meet-the-Experts program has been developed to create a channel by which early-career attendees can approach, interact and connect with mid- to late-career attendees to share intellect and experience.

Booth and Poster Tours: Mentors browse booths or view posters as they normally do, but with one or more mentees along to observe, participate and learn from experience.

Office Hours: Mentors will be available at tables in the Meet-the-Experts area of the Exhibit Hall where attendees can sign up to have a 10-15 minute chat about ... anything.

You can sign up at the congress to participate in one or more Meet-the-Experts activities (i.e., Booth Tour, Poster Tour, Office Hours).

Tuesday 18:00 - 19:00 Booth Tours
1st Floor Exhibit Hall
Wednesday 10:00 - 11:00 Poster Tours
1st Floor Exhibit Hall
Wednesday 15:30 - 16:30 Poster Tours
1st Floor Exhibit Hall
Wednesday 18:30 - 19:30 Office Hours Forum
1st Floor Cafe
Thursday 10:00 - 11:00 Poster Tours
1st Floor Exhibit Hall
Thursday 12:30 - 13:30 Poster Tours
1st Floor Exhibit Hall

Tim Collier, PhD
Quest Diagnostics-Cleveland HeartLab

Booth Tour on Tuesday @ 18:00
Office Hours on Wednesday @ 18:30
I've always had a passion for science, and have been fortunate to have excellent mentors at every stage of my career. I earned my Bachelor of Science Degree in Chemistry from North Carolina State University with research experience performing chemical analyses of preserved soft tissue extracted from Cretaceous fossils (yes, there was a T. rex!) under the mentorship of Prof. Mary H. Schweitzer.

My undergraduate research experience inspired me to continue my graduate studies with a focus in Bioanalytical Chemistry and Biotechnology under the mentorship of Prof. David Muddiman at the W. M. Keck FT-ICR Mass Spectrometry Laboratory, exploring quantitative proteomic methodologies in various biological systems ranging from fungal crop pathogens to human embryonic stem cell biology.

After completion of my doctoral program in 2010, I continued as a Post-Doctoral Research Scholar in the division of Molecular Oncology at Washington University School of Medicine in St. Louis, Missouri, in the lab of Prof. Ron Bose, and with additional mentorship from Prof. Michael Gross, where I developed quantitative phospho-proteomic and siRNA strategies to identify drug-resistance mechanisms in recurrent HER2 positive breast cancers. I also used mass spectrometry to study protein structure, and collaborated with experts with molecular dynamics simulations to produce the first heterodimer structures of HER2 and HER3 kinases, identifying structural relationships between tumor-driving mutations and unregulated signaling activity.

I currently reside in Cleveland, Ohio, as a Senior Research and Development Scientist at Quest Diagnostics-Cleveland HeartLab working with a dynamic team to develop diagnostic tests based on novel biomarkers to improve assessment of cardiovascular risk, including an assay that predicts lipoprotein function and is predictive of cardiovascular disease based on quantitative proteomics of High Density Lipoproteins (HDL).

Ravinder Singh, PhD
Mayo Clinic, MN, USA

Poster Tour 1 on Wednesday @ 10:00
Poster Tour 2 on Wednesday @ 15:30
Poster Tour 3 on Thursday @ 10:00
Poster Tour 4 on Thursday @ 12:30
Poster Judging on Thursday @ 10:00
Dr. Ravinder Singh PhD, DABCC, is professor of Laboratory Medicine and Pathology at the Mayo Clinic and is the Co-Director of the Endocrinology Laboratory at the Mayo Clinic. In 2000, he completed Clinical Chemistry fellowship at the Mayo Clinic. He is board-certified by the American Board of Clinical Chemistry and has published more than 200 papers in the area of lab diagnostics. He is member of various professional societies including AACC, and Endocrine Society. He has trained and mentored more than 30 clinical chemistry fellows. His areas of expertise is application of liquid chromatography tandem mass spectrometric (LC-MS/MS) to clinical laboratory analysis. Many of the methods which he has developed are now considered reference methods, and have subsequently been utilized for method standardization efforts. As a result, the clinical diagnosis of Cushing’s disease, pheochromocytoma and congenital adrenal hyperplasia have been improved. He has published his work on originally developed methods including such analytes as cortisol, synthetic corticosteroids, metanephrines, estradiol, vitamin D, and urine albumin amongst others. Dr. Singh is also the Co-PI of 3 grants. He is Co-director of the ICL lab which supports the Human research protocols. He was recently granted a Novel methodology CTSA award for “Development of Robust LC-MS/MS Based Methods for the Absolute Quantification of Proteins and Peptides.” And he was recently awarded AACC Outstanding Speaker Award, as well as MSACL Leadership Award for Mass Spectometry Applications to the clinical lab.

Judy Stone, PhD
Univ. of Calif. San Diego Helath

Office Hours on Wednesday @ 18:30
Judy Stone served as Asst. Professor and Assoc. Director of Clinical Chemistry at the University of Connecticut Health Center, as Asst. Professor and Director of the Core, Immunology and Toxicology Laboratories at the University of Massachusetts Medical Center; and has worked with mass spectrometry at Specialty Laboratories, San Francisco General Hospital and Kaiser Regional Laboratories in Northern California. She is currently Senior Technical Specialist in the Clinical Mass Spectrometry Laboratory, Center for Advanced Laboratory Medicine, Univ. of Calif. San Diego Health System.
Her research interests are in mass spectrometry applications and automation for clinical toxicology and endocrinology. She teaches, with a team of colleagues, a two day short course on “Getting Started with Quantitative LC-tandem MS in the Diagnostic Laboratory” at the MSACL meetings in the U.S. and Europe. She is a member of AACC and ASMS and serves as Chair, Board of Editors for the Mass Spectrometry Feature Series, Clinical Laboratory News.

Grace van der Gugten
St. Paul’s Hospital

Poster Judging on Thursday @ 10:00

Michael Vogeser, MD, PhD
Hospital of the University of Munich

Office Hours on Wednesday @ 18:30
Dr. Michael Vogeser, MD, is specialist in Laboratory Medicine and senior physician at the Hospital of the University of the Ludwig-Maximilians-University Munich, Germany (Institute of Laboratory Medicine). As an Associate Professor he is teaching Clinical Chemistry and Laboratory Medicine.The main scope of his scientific work isthe application of mass spectrometric technologies in routine clinical laboratory testing as translational diagnostics. Besides method development in therapeutic drug monitoring and endocrinology a further particular field of his work isquality and risk management in mass spectrometry and in clinical testing in general.Michael has published >150 articles in peer reviewed medical journals and is secretary of the German Association of Clinical Chemistry and Laboratory Medicine (DGKL) (2016 – 2019).

Manfred Wuhrer
Leiden University Medical Center

Office Hours on Wednesday @ 18:30
Prof. Manfred Wuhrer, PhD, Head of Center for Proteomics and Metabolomics, LUMC, Leiden

I studied Biochemistry at Regensburg University in Germany and obtained his PhD in 1999 at Giessen University. Subsequently, I joined the Leiden University Medical Center (LUMC; Leiden, The Netherlands) where I was appointed assistant professor in 2005 and associate professor in 2008. In 2013, I became full professor Analytics for Biomolecular Interactions at VU University, Amsterdam. In 2015 I continued my career as Head of Center for Proteomics and Metabolomics at LUMC. I focus on the development of mass spectrometric methods for glycomics and glycoproteomics, and their application in clinical research and biotechnology. Clinical applications cover the fields of rheumatoid arthritis, inflammatory bowel disease, colorectal cancer, prostate cancer, longevity, as well as various infectious diseases. I am coordinator of two Marie Curie Innovative Training Networks, GlyCoCan and GlySign, where early-stage researchers are trained with a special focus on bridging between academia and industry.